Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701230 | 0.87 | ALDH1A1 (0.66) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27845996 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22587515 | 0.86 | CYP1A2 (0.66) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3434183 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4103009 | 0.84 | MAPT (0.68) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14334518 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4697198 | 0.81 | HRH3 (0.53) | HRH3 | |
| SCHEMBL14207036 | 0.80 | CYP1A2 (0.61) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28485387 | 0.80 | CYP1A2 (0.61) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12639914 | 0.80 | ALDH1A1 (0.72) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603895-B1 | SUBSTITUTED BENZOYLUREIDOPYRIDYL-PIPERIDINE AND -PYRROLIDINE CARBOXYLIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-02-20 | — | — | EP | disclosed |
| EP-1603895-A1 | SUBSTITUTED BENZOYLUREIDOPYRIDYL-PIPERIDINE AND -PYRROLIDINE CARBOXYLIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF | Sanofi-Aventis Deutschland GmbH (DE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004078743-A1 | SUBSTITUTED BENZOYLUREIDOPYRIDYL-PIPERIDINE AND -PYRROLIDINE CARBOXYLIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-09-16 | — | — | WO | disclosed |