Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201640 | 0.81 | INSR (0.41) | MEN1NPC1USP2RAB9AKMT2A | |
| SCHEMBL61983 | 0.80 | MEN1 (0.35) | MEN1NPC1USP2APOBEC3ARAB9A | |
| SCHEMBL13201623 | 0.68 | GAA (0.44) | MEN1NPC1USP2APOBEC3ARAB9A | |
| SCHEMBL61432 | 0.67 | GAA (0.46) | MEN1NPC1USP2APOBEC3ARAB9A | |
| SCHEMBL61942 | 0.62 | GAA (0.35) | — | |
| SCHEMBL13263427 | 0.61 | MAPT (0.48) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL13232715 | 0.61 | GAA (0.34) | — | |
| SCHEMBL61437 | 0.60 | ALDH1A1 (0.35) | MEN1USP2KMT2A | |
| SCHEMBL62619 | 0.60 | GAA (0.35) | — | |
| SCHEMBL62459 | 0.60 | INSR (0.47) | MEN1NPC1USP2RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767821-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2010-08-03 | — | — | US | disclosed |
| US-7563891-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2009-07-21 | — | — | US | disclosed |