Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | PTPRC | P08575 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363187 | 1.00 | MEN1 (0.49) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL13220107 | 0.79 | POLB (0.40) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23392597 | 0.78 | PTPRC (0.44) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL16270911 | 0.78 | PTPRC (0.44) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL13220112 | 0.76 | ALDH1A1 (0.37) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL21940524 | 0.74 | CMA1 (0.34) | CMA1 | |
| SCHEMBL21940345 | 0.74 | CMA1 (0.34) | CMA1 | |
| SCHEMBL7180359 | 0.73 | MEN1 (0.53) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL4543564 | 0.71 | KDM4E (0.55) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL4543566 | 0.71 | KDM4E (0.55) | MEN1KMT2AKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131193-A1 | PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2020-04-30 | — | — | US | disclosed |
| US-20100214373-A1 | AUTHENTICATING A PRODUCT | AUTHENTIX, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100214373-A1 | AUTHENTICATING A PRODUCT | AUTHENTIX, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| US-7776767-B2 | Lattice intended for the constitution of a light-attenuation screen, with self-regulation of the transmitted light | XLSCREEN S.A.S. (FR) | 2010-08-17 | — | — | US | disclosed |
| US-7776767-B2 | Lattice intended for the constitution of a light-attenuation screen, with self-regulation of the transmitted light | XLSCREEN S.A.S. (FR) | 2010-08-17 | — | — | US | disclosed |
| WO-2009017506-A2 | AUTHENTICATING A PRODUCT | AUTHENTIX, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| US-20080166518-A1 | Lattice intended for the constitution of a light-attenuation screen, with self-regulation of the transmitted light | XLSCREEN S.A.S. | 2008-07-10 | — | — | US | disclosed |
| US-20080166518-A1 | Lattice intended for the constitution of a light-attenuation screen, with self-regulation of the transmitted light | XLSCREEN S.A.S. | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131193-A1 | PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES | PPOX, TYR, NQO1 | MEN1 4353/4885KMT2A 1829/4885KDM4E 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.