Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPRA | P18433 | 1/20 | 0.50 |
| ▸ | PTPRB | P23467 | 1/20 | 0.50 |
| ▸ | PTPRE | P23469 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28904215 | 0.84 | PTPRC (0.39) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL7715 | 0.83 | IDO1 (0.49) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL30748562 | 0.83 | IDO1 (0.49) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL12806404 | 0.81 | PTPRC (0.37) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL522679 | 0.79 | PTPN1 (0.55) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL12671441 | 0.79 | PTGS2 (0.51) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL17307119 | 0.78 | PTPRC (0.34) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL7903905 | 0.78 | MAP2K2 (0.41) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL12240241 | 0.78 | CA12 (0.43) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL223101 | 0.77 | CSNK2A1 (0.65) | MCL1ALDH1A1KDM4EHPGDCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683593-B | Preparation method of canagliflozin intermediate and application of canagliflozin intermediate in preparation of canagliflozin | 湖北石河医药科技有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-113683593-A | Preparation method of canagliflozin intermediate and application of canagliflozin intermediate in preparation of canagliflozin | 湖北石河医药科技有限公司 | 2021-11-23 | — | — | CN | claimed |
| CN-213000621-U | 5-iodine-2-methyl benzoic acid centrifugal device | 江苏恒洲化工有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-213020600-U | 5-iodine-2-methyl benzoic acid drying device | 江苏恒洲化工有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-210906154-U | Reaction unit is used in production of 5-iodine-2-methyl benzoic acid | 江苏恒洲化工有限公司 | 2020-07-03 | — | — | CN | claimed |
| EP-3059220-B1 | METHOD OF PREPARING AND RECOVERING 2-METHYL-5-IODOBENZOIC ACID | ABA CHEMICALS CORP (CN) | 2018-12-05 | — | — | EP | claimed |
| CN-107652175-A | A kind of synthetic method of the iodo-benzoic acid of 2 methyl 5 | 宁波人健化学制药有限公司 | 2018-02-02 | — | — | CN | claimed |
| EP-3059220-A1 | METHOD OF PREPARING AND RECOVERING 2-METHYL-5-IODOBENZOIC ACID | ABA Chemicals Corporation (CN) | 2016-08-24 | — | — | EP | claimed |
| CN-103539662-B | Preparation and recovery method of 2-methyl-5-iodobenzoic acid | ABA CHEMICALS CORP | 2015-04-08 | — | — | CN | claimed |
| CN-103539662-A | Preparation and recovery method of 2-methyl-5-iodobenzoic acid | ABA CHEMICALS CORP | 2014-01-29 | — | — | CN | claimed |
| EP-1595862-B1 | PROCESS FOR PRODUCTION OF IODINE COMPOUNDS AND PROCESS FOR PRODUCTION OF HIGH-PURITY 5-IODO-2-METHYLBENZOIC ACID | MITSUBISHI GAS CHEMICAL CO (JP) | 2010-11-17 | — | — | EP | claimed |
| EP-1642881-B1 | PROCESS FOR PRODUCING 5-IODO-2-METHYLBENZOIC ACID | MITSUBISHI GAS CHEMICAL CO (JP) | 2010-10-27 | — | — | EP | claimed |
| US-7750182-B2 | Process for production of iodine compounds and process for production of high-purity 5-iodo-2-methylbenzoic acid | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2010-07-06 | — | — | US | claimed |
| US-7642374-B2 | Process for producing 5-iodo-2-methylbenzoic acid | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2010-01-05 | — | — | US | claimed |
| US-20060167312-A1 | Process for producing 5-iodo-2-methylbenzoic acid | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-07-27 | — | — | US | claimed |
| US-20060161028-A1 | Process for production of iodine compounds and process for production of high-purity 5-iodo-2-methylbenzoic acid | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-07-20 | — | — | US | claimed |
| EP-1642881-A1 | PROCESS FOR PRODUCING 5-IODO-2-METHYLBENZOIC ACID | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-04-05 | — | — | EP | claimed |
| EP-1595862-A1 | PROCESS FOR PRODUCTION OF IODINE COMPOUNDS AND PROCESS FOR PRODUCTION OF HIGH-PURITY 5-IODO-2-METHYLBENZOIC ACID | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-11-16 | — | — | EP | claimed |
| US-12617789-B2 | Small molecular inhibitors of NF-κb inducing kinase | JANSSEN PHARMACEUTICA NV (BE) | 2026-05-05 | — | — | US | disclosed |
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617789-B2 | Small molecular inhibitors of NF-κb inducing kinase | IRAK3, IKBKB, IKBKG | PTPRC 209/4885PTPN2 196/4885PTPN1 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.