⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130275 | 0.93 | — | — | |
| SCHEMBL4418854 | 0.90 | ALDH1A1 (0.33) | — | |
| SCHEMBL4416587 | 0.90 | ALDH1A1 (0.33) | — | |
| SCHEMBL4417953 | 0.90 | ALDH1A1 (0.33) | — | |
| SCHEMBL4416531 | 0.90 | ALDH1A1 (0.33) | — | |
| SCHEMBL4419210 | 0.90 | ALDH1A1 (0.33) | — | |
| SCHEMBL493926 | 0.90 | — | — | |
| SCHEMBL4416288 | 0.90 | ALDH1A1 (0.33) | — | |
| SCHEMBL21869877 | 0.90 | ALDH1A1 (0.33) | — | |
| SCHEMBL4416520 | 0.90 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120295-A | N-substituted imidazole formate derivative and application thereof | 成都麻沸散医药科技有限公司 | 2023-05-16 | — | — | CN | disclosed |
| US-11434205-B2 | Substituted imidazole carboxylate derivatives and the use thereof | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2022-09-06 | — | — | US | disclosed |
| WO-2021191872-A1 | HETEROARYL-SUBSTITUTED MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | Janssen Biopharma, Inc. (US) | 2021-09-30 | — | — | WO | disclosed |
| EP-3747869-A1 | SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3747869-A1 | SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-12-09 | — | — | EP | disclosed |
| US-20200369621-A1 | SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-11-26 | — | — | US | disclosed |
| US-20200369621-A1 | SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-11-26 | — | — | US | disclosed |
| WO-2019149228-A1 | SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF | 成都安诺晨创医药科技有限公司 | 2019-08-08 | — | — | WO | disclosed |
| CN-109776512-A | N-substituted imidazole formate derivative and application thereof | 成都安诺晨创医药科技有限公司 | 2019-05-21 | — | — | CN | disclosed |
| EP-2686369-B1 | MULTIFUNCTIONAL SULFUR-CONTAINING POLYMERS, COMPOSITIONS THEREOF AND METHODS OF USE | PRC DESOTO INT INC (US) | 2018-12-19 | — | — | EP | disclosed |
| EP-1278742-A1 | CHROMENYLMETHYLPYRIMIDINEDIAMINES AS ANTIBACTERIAL AGENTS | Basilea Pharmaceutica AG (CH) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001083476-A1 | CHROMENYLMETHYL PYRIMIDINEDIAMINES AS ANTIBACTERIAL AGENTS | BASILEA PHARMACEUTICA AG (CH) | 2001-11-08 | — | — | WO | disclosed |
| US-5607960-A | Indole derivatives as 5-HT1-like agonists for use in migraine | PFIZER INC. (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0695301-B1 | INDOLE DERIVATIVES AS 5-HT1-LIKE AGONISTS FOR USE IN MIGRAINE | PFIZER LTD (GB) | 1996-10-30 | — | — | EP | disclosed |
| CN-1121348-A | Indole derivatives as 5-H1-like agonists for use in migraine | PFIZER RES & DEV (IE) | 1996-04-24 | — | — | CN | disclosed |
| EP-0695301-A1 | INDOLE DERIVATIVES AS 5-H1-LIKE AGONISTS FOR USE IN MIGRAINE | PFIZER LTD (GB) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994024127-A1 | INDOLE DERIVATIVES AS 5-H1-LIKE AGONISTS FOR USE IN MIGRAINE | PFIZER LIMITED (GB) | 1994-10-27 | — | — | WO | disclosed |
| US-4206140-A | INSECTICIDES, ANTHELMINTICS | ROUSSEL UCLAF (FR) | 1980-06-03 | — | — | US | disclosed |
| US-4101574-A | Cyclopropanecarboxylic acid chlorides | ROUSSEL UCLAF (FR) | 1978-07-18 | — | — | US | disclosed |
| US-3997586-A | Cyclopropanecarboxylic acids and esters | ROUSSEL-UCLAF (FR) | 1976-12-14 | — | — | US | disclosed |