SCHEMBL13209223

SCHEMBL13209223

Cc1ccnc2c1sc1ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 1/20 0.51
CDK5 Q00535 1/20 0.51
CDK5R1 Q15078 1/20 0.51
MAPT P10636 2/20 0.46
HRH4 Q9H3N8 1/20 0.44
CCR1 P32246 1/20 0.44
CCR5 P51681 1/20 0.44
CCR8 P51685 1/20 0.44
EGFR P00533 4/20 0.43
PSMD14 O00487 1/20 0.43
COPS5 Q92905 1/20 0.43
HTR2C P28335 1/20 0.41
ROCK1 Q13464 1/20 0.41
TNKS O95271 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
KRAS P01116 1/20 0.40
PIK3CA P42336 1/20 0.40
GPR3 P46089 1/20 0.40
CYP2A6 P11509 1/20 0.40
HCRTR1 O43613 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22874230 0.81 LIMK1 (0.54) LIMK1CDK5CDK5R1MAPTHRH4
SCHEMBL19039387 0.80 PSMD14 (0.49) LIMK1MAPTCCR1CCR5CCR8
SCHEMBL16919865 0.80 LIMK1 (0.56) LIMK1MAPTCCR1CCR5CCR8
SCHEMBL16919850 0.80 LIMK1 (0.59) LIMK1MAPTCCR1CCR5CCR8
SCHEMBL16919848 0.80 LIMK1 (0.59) LIMK1
SCHEMBL16919869 0.79 CCR1 (0.41) LIMK1CDK5CDK5R1CCR1CCR5
SCHEMBL16919864 0.79 CCR1 (0.41) LIMK1CDK5CDK5R1MAPTCCR1
SCHEMBL19937109 0.79 LIMK1 (0.51) LIMK1CDK5CDK5R1MAPTHRH4
SCHEMBL16693325 0.79 LIMK1 (0.51) LIMK1CDK5CDK5R1MAPTHRH4
SCHEMBL16685432 0.79 LIMK1 (0.51) LIMK1CDK5CDK5R1MAPTHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-01 US disclosed
US-20210367162-A1 HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 US disclosed
US-20200274081-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-27 US disclosed
US-10208026-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-02-19 US disclosed
WO-2018043761-A1 SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES IDEMITSU KOSAN CO.,LTD. (JP) 2018-03-08 WO disclosed
EP-3063153-B1 AZADIBENZOTHIOPHENES FOR ELECTRONIC APPLICATIONS IDEMITSU KOSAN CO (JP) 2018-03-07 EP disclosed
US-9735373-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-08-15 US disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 US disclosed
US-20160141525-A1 ORGANIC LIGHT-EMITTING MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-19 US disclosed
US-20150266863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-24 US disclosed
US-20150266863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-24 US disclosed
US-20150243893-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 US disclosed
US-20150207082-A1 ORGANIC MATERIALS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2015-07-23 US disclosed
US-20150207082-A1 ORGANIC MATERIALS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2015-07-23 US disclosed
US-20140361252-A1 ALUMINUM CHELATES AS MATERIALS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2014-12-11 US disclosed
US-7786131-B2 Anticancer agents; restenosis; atherosclerosis; skin disorders WARNER-LAMBERT COMPANY (US) 2010-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160141525-A1 ORGANIC LIGHT-EMITTING MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBPL3 LIMK1 1441/4885CDK5 1187/4885CDK5R1 2622/4885
US-20230389413-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 LIMK1 2662/4885CDK5 4422/4885CDK5R1 2560/4885
US-20200274081-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 LIMK1 2662/4885CDK5 4422/4885CDK5R1 2560/4885
US-20150207082-A1 ORGANIC MATERIALS FOR OLEDS OCIAD1, OCIAD2, SLC25A21 LIMK1 4180/4885CDK5 1881/4885CDK5R1 2734/4885
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE CHRM1, CHRM2, CHRM4 LIMK1 1044/4885CDK5 1467/4885CDK5R1 1378/4885
US-10208026-B2 Organic electroluminescent materials and devices ZYX, LBR, LOXL1 LIMK1 259/4885CDK5 4424/4885CDK5R1 4187/4885
US-20150266863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ZYX, LBR, LOXL1 LIMK1 259/4885CDK5 4424/4885CDK5R1 4187/4885
US-11758807-B2 Organic electroluminescent materials and devices GLRA3, ESRRG, GLRA1 LIMK1 2662/4885CDK5 4422/4885CDK5R1 2560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.