Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753879 | 0.85 | PARP1 (0.68) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL12287066 | 0.83 | PARP1 (0.61) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL2092812 | 0.81 | PARP1 (0.69) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL5854006 | 0.80 | CA12 (0.55) | PARP1MEN1KMT2ATDP1MAPT | |
| SCHEMBL2060236 | 0.79 | PARP1 (0.61) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL3753584 | 0.79 | CES2 (0.65) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL31529061 | 0.79 | CES2 (0.65) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL29922789 | 0.79 | PARP1 (0.61) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL29639739 | 0.79 | PARP1 (0.65) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL29444189 | 0.79 | PARP1 (0.54) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781519-B2 | Solubilizer and composition containing same | KUREHA CORPORATION (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20070244221-A1 | Solubilizer and Composition Containing Same | KUREHA CORPORATION (JP) | 2007-10-18 | — | — | US | disclosed |