Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29373697 | 0.83 | NR4A1 (0.57) | CNR2ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL690407 | 0.83 | NR4A1 (0.57) | CNR2ALDH1A1MAPTHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL5415206 | 0.81 | NR4A1 (0.55) | CNR2ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL2152502 | 0.81 | ALDH1A1 (0.56) | CNR2ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL11689360 | 0.81 | PLK1 (0.62) | CNR2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL9038317 | 0.80 | CNR2 (0.45) | CNR2ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL38665356 | 0.79 | MAPT (0.62) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL6362640 | 0.79 | CYP1A2 (0.53) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL10909445 | 0.79 | CDC25B (0.60) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL25986589 | 0.79 | MAPT (0.62) | ALDH1A1MAPTHPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836201-B1 | PYRROLIDINE INHIBITORS OF IAP | GENENTECH INC (US) | 2010-08-11 | — | — | EP | disclosed |