Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.64 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | PLG | P00747 | 1/20 | 0.61 |
| ▸ | PLAU | P00749 | 1/20 | 0.61 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15788186 | 0.95 | MAPK14 (0.66) | NAMPTHTTNR1H4GRM4MEN1 | |
| SCHEMBL2173418 | 0.93 | HTT (0.71) | NAMPTHTTNR1H4GRM4MEN1 | |
| SCHEMBL94618 | 0.92 | NAMPT (0.59) | NAMPTHTTNR1H4GRM4MEN1 | |
| SCHEMBL6655548 | 0.92 | KMT2A (0.66) | NAMPTHTTNR1H4GRM4MEN1 | |
| SCHEMBL14187585 | 0.91 | PTGS1 (0.62) | NAMPTHTTNR1H4GRM4MEN1 | |
| SCHEMBL7300564 | 0.90 | NR1H4 (0.80) | NAMPTHTTNR1H4GRM4MEN1 | |
| SCHEMBL666216 | 0.89 | MAPK14 (0.74) | NR1H4MEN1KMT2AALDH1A1MAPK14 | |
| SCHEMBL1247713 | 0.87 | NPC1 (0.71) | NAMPTHTTNR1H4GRM4MEN1 | |
| SCHEMBL3786489 | 0.85 | NR1H4 (0.57) | NAMPTHTTNR1H4GRM4MEN1 | |
| SCHEMBL14082881 | 0.85 | MEN1 (0.58) | NAMPTHTTNR1H4GRM4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250275537-A1 | CARBOXAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2025-09-04 | — | — | US | disclosed |
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | THE GENETICS COMPANY, INC. (CH) | 2010-08-12 | — | — | US | disclosed |
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | THE GENETICS COMPANY, INC. (CH) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | CBR3, CYCS, CYC1 | NAMPT 3166/4885HTT 3170/4885NR1H4 759/4885 |
| US-20250275537-A1 | CARBOXAMIDE APYRASE INHIBITORS | APEH, CNDP2, DNPEP | NAMPT 847/4885HTT 4613/4885NR1H4 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.