Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | F2 | P00734 | 1/20 | 0.71 |
| ▸ | PLG | P00747 | 1/20 | 0.71 |
| ▸ | PLAU | P00749 | 1/20 | 0.71 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.71 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.69 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.69 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.65 |
| ▸ | NAMPT | P43490 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210705 | 0.93 | NAMPT (0.66) | HTTF2PLGPLAUKLKB1 | |
| SCHEMBL31219284 | 0.90 | HTT (0.62) | HTTF2PLGPLAUKLKB1 | |
| SCHEMBL15788186 | 0.89 | MAPK14 (0.66) | HTTF2PLGPLAUKLKB1 | |
| SCHEMBL6655548 | 0.86 | KMT2A (0.66) | HTTF2PLGPLAUKLKB1 | |
| SCHEMBL94618 | 0.86 | NAMPT (0.59) | HTTF2PLGPLAUKLKB1 | |
| SCHEMBL7379264 | 0.85 | KCNK3 (0.71) | KCNK3KCNK9ALDH1A1MAPTSIRT1 | |
| SCHEMBL14187585 | 0.85 | PTGS1 (0.62) | HTTF2PLGPLAUKLKB1 | |
| Hydrochloric Acid SCHEMBL2104599 | 0.85 | HTT (0.60) | HTTF2PLGPLAUKLKB1 | |
| SCHEMBL4252916 | 0.85 | KCNK3 (0.72) | KCNK3KCNK9MAPTMEN1KMT2A | |
| SCHEMBL5612900 | 0.84 | KCNK3 (0.69) | KCNK3KCNK9SIRT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006035-B1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | NEUPHARMA INC (US) | 2023-11-22 | — | — | EP | claimed |
| EP-1068187-A1 | PYRAZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999051580-A1 | PYRAZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES (US) | 1999-10-14 | — | — | WO | claimed |
| US-12269814-B2 | Process for preparing a compound useful to treat mycoses | PULMOCIDE LIMITED (GB) | 2025-04-08 | — | — | US | disclosed |
| US-11661415-B2 | Process for preparing a compound useful to treat mycoses | PULMOCIDE LIMITED (GB) | 2023-05-30 | — | — | US | disclosed |
| US-20110172203-A1 | Substituted Imidazopyridinyl-Aminopyridine Compounds | ARQULE, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| WO-2011082270-A2 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ARQULE. INC. (US) | 2011-07-07 | — | — | WO | disclosed |
| CN-100335468-C | Diaryl amidine compound, its production, medicinal composition and use | DRUG INST CHINESE ACADEMY OF M (CN) | 2007-09-05 | — | — | CN | disclosed |
| CN-1712398-A | Diaryl amidine compound, its production, medicinal composition and use | DRUG INST CHINESE ACADEMY OF M (CN) | 2005-12-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661415-B2 | Process for preparing a compound useful to treat mycoses | DPM1, CYP51A1, ERG28 | HTT 4807/4885F2 196/4885PLG 2030/4885 |
| US-20110172203-A1 | Substituted Imidazopyridinyl-Aminopyridine Compounds | MKI67, CDK4, ABL1 | HTT 939/4885F2 4072/4885PLG 4254/4885 |
| US-12269814-B2 | Process for preparing a compound useful to treat mycoses | C1R, CBR1, CBR3 | HTT 1887/4885F2 2967/4885PLG 4638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.