Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13117512 | 0.86 | VDR (0.44) | VDRCD274RARBTTRCYP1A2 | |
| SCHEMBL13213353 | 0.85 | VDR (0.34) | VDRCD274PDCD1 | |
| SCHEMBL13140331 | 0.83 | VDR (0.42) | VDRCD274RARBTTRCYP1A2 | |
| SCHEMBL13117715 | 0.79 | CD274 (0.40) | CD274PDCD1RAB9A | |
| SCHEMBL13117432 | 0.78 | MAPT (0.41) | VDRCD274TTRCYP1A2CYP2C8 | |
| SCHEMBL13139845 | 0.72 | CD274 (0.50) | CD274RARBPDCD1 | |
| SCHEMBL2907674 | 0.71 | FFAR1 (0.52) | CD274 | |
| SCHEMBL13117528 | 0.70 | CD274 (0.44) | VDRCD274PDCD1 | |
| SCHEMBL12577844 | 0.70 | CD274 (0.41) | VDRCD274PDCD1 | |
| SCHEMBL12004138 | 0.70 | CD274 (0.39) | VDRCD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216330-A1 | OXADIAZOLIDINEDIONE COMPOUND | Astellas Pharma Inc. (JP) | 2010-08-11 | — | — | EP | disclosed |