Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13213376 | 0.85 | VDR (0.36) | VDRCD274PDCD1 | |
| SCHEMBL13117528 | 0.85 | CD274 (0.44) | VDRCD274PDCD1IDO1 | |
| SCHEMBL13117714 | 0.77 | CD274 (0.39) | CD274PDCD1 | |
| SCHEMBL13213459 | 0.73 | TDP1 (0.36) | CD274PDCD1 | |
| SCHEMBL13117512 | 0.70 | VDR (0.44) | VDRCD274PDCD1 | |
| SCHEMBL13139660 | 0.70 | CD274 (0.54) | CD274PDCD1IDO1 | |
| SCHEMBL13117737 | 0.70 | CD274 (0.41) | CD274PDCD1 | |
| SCHEMBL2912862 | 0.69 | FFAR1 (0.50) | CD274PDCD1 | |
| SCHEMBL9964446 | 0.69 | CD274 (0.40) | VDRCD274PDCD1 | |
| SCHEMBL13213383 | 0.69 | CD274 (0.36) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216330-A1 | OXADIAZOLIDINEDIONE COMPOUND | Astellas Pharma Inc. (JP) | 2010-08-11 | — | — | EP | disclosed |