Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MYOC | Q99972 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433 | 0.83 | HSPB1 (0.52) | HSPB1CA1CA2CA9CES2 | |
| SCHEMBL28135398 | 0.82 | HSPB1 (0.50) | HSPB1CA1CA2CA9CES2 | |
| Hydrochloric Acid SCHEMBL27912110 | 0.82 | HSPB1 (0.50) | HSPB1CA1CA2CA9CES2 | |
| Ammonia Solution, Strong SCHEMBL27663814 | 0.82 | HSPB1 (0.50) | HSPB1CA1CA2CA9CES2 | |
| SCHEMBL13665383 | 0.82 | HSPB1 (0.55) | HSPB1CA1CA2CA9CES2 | |
| Hydrazine SCHEMBL27959578 | 0.78 | CA1 (0.50) | HSPB1CA1CA2CA9CES2 | |
| SCHEMBL535259 | 0.78 | HSD17B10 (0.50) | HSPB1CA1CA2CA9CES2 | |
| SCHEMBL5847950 | 0.78 | HSPB1 (0.50) | HSPB1CA1CA2CA9CES2 | |
| SCHEMBL28049499 | 0.78 | HSPB1 (0.50) | HSPB1CA1CA2CA9CES2 | |
| SCHEMBL28049513 | 0.78 | HSPB1 (0.50) | HSPB1CA1CA2CA9CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420850-B2 | Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers | Iberhospitex, S.A (ES) | 2013-04-16 | — | — | US | disclosed |
| US-20120059117-A1 | COMPOUNDS FOR THE SYNTHESIS OF BIOSTABLE POLYURETHANE, POLYUREA OR POLYUREA URETHANE POLYMERS | IBERHOSPITEX, S.A. | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059117-A1 | COMPOUNDS FOR THE SYNTHESIS OF BIOSTABLE POLYURETHANE, POLYUREA OR POLYUREA URETHANE POLYMERS | PUF60, UMPS, UGP2 | HSPB1 3231/4885CA1 3362/4885CA2 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.