Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 7/20 | 0.50 |
| ▸ | MMP2 | P08253 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653509 | 0.87 | CDK1 (0.54) | CDK1CCNB1ALOX15RAB9AKDM4E | |
| SCHEMBL1653769 | 0.85 | CDK1 (0.61) | CDK1CCNB1ALOX15RAB9AKDM4E | |
| SCHEMBL18131117 | 0.85 | CDK1 (0.52) | CDK1CCNB1ALOX15RAB9AKDM4E | |
| SCHEMBL13684403 | 0.82 | CDK1 (0.54) | CDK1CCNB1ALOX15RAB9AKDM4E | |
| SCHEMBL18131096 | 0.81 | ALDH1A1 (0.54) | CDK1CCNB1ALOX15RAB9AKDM4E | |
| SCHEMBL656252 | 0.79 | ALDH1A1 (0.58) | CDK1CCNB1ALOX15RAB9AKDM4E | |
| SCHEMBL4043989 | 0.78 | CDK1 (0.56) | CDK1CCNB1ALOX15RAB9AKDM4E | |
| SCHEMBL20604982 | 0.77 | RAB9A (0.57) | CDK1CCNB1ALOX15RAB9AKDM4E | |
| SCHEMBL5356682 | 0.77 | CDK1 (0.55) | CDK1CCNB1ALOX15RAB9AKDM4E | |
| SCHEMBL4045178 | 0.76 | CDK1 (0.54) | CDK1CCNB1ALOX15RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7777047-B2 | Indole compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-17 | — | — | US | disclosed |