Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TK1 | P04183 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | TK2 | O00142 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25470065 | 0.93 | TK1 (0.57) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL8925580 | 0.92 | TK1 (0.59) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL8925599 | 0.92 | TK1 (0.59) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL8926757 | 0.90 | TK1 (0.52) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL8926762 | 0.90 | TK1 (0.52) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL29757418 | 0.90 | TK1 (0.58) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL18214117 | 0.88 | LMNA (0.59) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL21585062 | 0.88 | LMNA (0.59) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL2611574 | 0.88 | LMNA (0.59) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL2030383 | 0.88 | LMNA (0.59) | LMNASMN1; SMN2TK1ALOX12ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7771973-B2 | sequencing reactions where nucleotide or nucleoside molecules modified by reversible covalent attachment of 3'-OH blocking groups thereto, are used where blocked nucleotide or nucleoside molecules are required | ILLUMINA CAMBRIDGE LIMITED (GB) | 2010-08-10 | — | — | US | disclosed |
| US-20090325172-A1 | Modified nucleotides | SOLEXA LIMITED | 2009-12-31 | — | — | US | disclosed |