Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.49 |
| ▸ | TUBB | P07437 | 4/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.49 |
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12593827 | 0.89 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10030786 | 0.89 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12810366 | 0.87 | TUBB1 (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17145723 | 0.84 | TUBB1 (0.60) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10030791 | 0.84 | TUBB1 (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13456507 | 0.83 | APP (0.57) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13223338 | 0.82 | TUBB1 (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12774239 | 0.82 | TUBB1 (0.63) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29814897 | 0.80 | TUBB1 (0.76) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1414725 | 0.80 | TUBB1 (0.76) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786098-B2 | Fluoroalkoxycombretastatin derivatives, method for producing the same and use thereof | ZHEJIANG DADE PHARMACEUTICAL GROUP CO. LTD. (CN) | 2010-08-31 | — | — | US | disclosed |
| US-20080306027-A1 | Fluoroalkoxycombretastatin Derivatives, Method For Producing the Same and Use Thereof | ZHEJIANG DADE PHARMACEUTICAL GROUP CO., LTD. (CN) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306027-A1 | Fluoroalkoxycombretastatin Derivatives, Method For Producing the Same and Use Thereof | TUBB, TUBB1, TUBB3 | TUBB1 2/4885TUBB4A 7/4885TUBB 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.