Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 3/20 | 0.47 |
| ▸ | NPY1R | P25929 | 2/20 | 0.47 |
| ▸ | NPY2R | P49146 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13224412 | 0.94 | OPRK1 (0.47) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11048780 | 0.87 | OPRK1 (0.51) | OPRK1GHSR | |
| SCHEMBL13224316 | 0.84 | F2 (0.45) | GHSR | |
| SCHEMBL13224318 | 0.84 | F2 (0.45) | GHSR | |
| SCHEMBL13224313 | 0.84 | F2 (0.45) | GHSR | |
| SCHEMBL11045721 | 0.84 | OPRK1 (0.50) | OPRK1GHSR | |
| SCHEMBL11045505 | 0.84 | OPRK1 (0.50) | OPRK1GHSR | |
| SCHEMBL31181266 | 0.82 | GNPAT (0.59) | FURINOPRK1 | |
| SCHEMBL22133134 | 0.81 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30497071 | 0.81 | GNPAT (0.58) | FURINOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8884214-B2 | Methods of using halogenated peptides as internal standards for liquid chromatography-mass spectrometry | INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2014-11-11 | — | — | US | disclosed |
| US-8884214-B2 | Methods of using halogenated peptides as internal standards for liquid chromatography-mass spectrometry | INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130193317-A1 | METHODS OF USING HALOGENATED PEPTIDES AS INTERNAL STANDARDS FOR LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY | INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130193317-A1 | METHODS OF USING HALOGENATED PEPTIDES AS INTERNAL STANDARDS FOR LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY | INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2013-08-01 | — | — | US | disclosed |
| US-8324347-B2 | Methods of using halogenated peptides as internal standards for liquid chromatography-mass spectrometry | INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2012-12-04 | — | — | US | disclosed |
| US-8324347-B2 | Methods of using halogenated peptides as internal standards for liquid chromatography-mass spectrometry | INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2012-12-04 | — | — | US | disclosed |
| US-20100216180-A1 | METHODS OF USING HALOGENATED PEPTIDES AS INTERNAL STANDARDS FOR LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY | INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216180-A1 | METHODS OF USING HALOGENATED PEPTIDES AS INTERNAL STANDARDS FOR LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY | INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216180-A1 | METHODS OF USING HALOGENATED PEPTIDES AS INTERNAL STANDARDS FOR LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY | PTMS, VIP, SRMS | FURIN 698/4885OPRK1 4195/4885NPY4R 1119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.