SCHEMBL1322709

SCHEMBL1322709

CC(C)(C)C(c1ccc(O)cc1)(c1ccc(O)cc1)C(C)(C)C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.62
ESR2 Q92731 11/20 0.62
CYP3A4 P08684 4/20 0.62
LMNA P02545 2/20 0.62
TYR P14679 2/20 0.62
HPGD P15428 2/20 0.62
HSD17B10 Q99714 2/20 0.62
AR P10275 1/20 0.62
TSHR P16473 1/20 0.62
SLC6A2 P23975 1/20 0.62
SLC6A4 P31645 1/20 0.62
HTR6 P50406 1/20 0.62
ESRRG P62508 1/20 0.62
SLC6A3 Q01959 1/20 0.62
ALDH1A1 P00352 3/20 0.52
SHBG P04278 1/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2799338 0.91 ESR1 (0.68) ESR1ESR2CYP3A4LMNATYR
SCHEMBL9576036 0.84 ESR1 (0.50) ESR1ESR2CYP3A4LMNATYR
SCHEMBL462888 0.80 ESR1 (0.46) ESR1ESR2CYP3A4LMNATYR
SCHEMBL313073 0.78 ESR1 (0.62) ESR1ESR2CYP3A4LMNATYR
SCHEMBL31544540 0.78 ESR1 (0.62) ESR1ESR2CYP3A4LMNATYR
SCHEMBL9844421 0.78 ESR1 (0.62) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL3170263 0.77 ESR1 (1.00) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL15062 0.77 ESR1 (1.00) ESR1ESR2CYP3A4LMNATYR
SCHEMBL9454476 0.77 ESR1 (0.68) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL9774987 0.77 ESR1 (1.00) ESR1ESR2CYP3A4LMNATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213652-B Preparation method of vinyl-terminated polyphenyl ether compound 河北健馨生物科技有限公司 2023-08-08 CN disclosed
CN-114213652-A Preparation method of vinyl-terminated polyphenyl ether compound 河北健馨生物科技有限公司 2022-03-22 CN disclosed
US-8058333-B1 Flame retarding composite material ENTIRE TECHNOLOGY CO., LTD. (TW) 2011-11-15 US disclosed
US-8058333-B1 Flame retarding composite material ENTIRE TECHNOLOGY CO., LTD. (TW) 2011-11-15 US disclosed
US-8058333-B1 Flame retarding composite material ENTIRE TECHNOLOGY CO., LTD. (TW) 2011-11-15 US disclosed
EP-0323086-A2 Process for preparing detergents EXXON CHEMICAL PATENTS INC. (US) 1989-07-05 EP disclosed