SCHEMBL9454476

SCHEMBL9454476

CC(c1ccc(O)cc1)(c1ccc(O)cc1)C(C)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.68
ESR2 Q92731 11/20 0.68
CYP3A4 P08684 4/20 0.68
LMNA P02545 2/20 0.68
TYR P14679 2/20 0.68
HPGD P15428 2/20 0.68
HSD17B10 Q99714 2/20 0.68
AR P10275 1/20 0.68
TSHR P16473 1/20 0.68
SLC6A2 P23975 1/20 0.68
SLC6A4 P31645 1/20 0.68
HTR6 P50406 1/20 0.68
ESRRG P62508 1/20 0.68
SLC6A3 Q01959 1/20 0.68
ALDH1A1 P00352 3/20 0.56
SHBG P04278 1/20 0.54
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313073 0.88 ESR1 (0.62) ESR1ESR2CYP3A4LMNATYR
SCHEMBL6576495 0.86 ESR1 (0.59) ESR1ESR2CYP3A4LMNATYR
SCHEMBL3685250 0.84 ESR1 (0.58) ESR1ESR2CYP3A4LMNATYR
SCHEMBL136609 0.84 ESR1 (0.56) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL3170263 0.81 ESR1 (1.00) ESR1ESR2CYP3A4LMNATYR
SCHEMBL677795 0.81 ESR1 (0.68) ESR1ESR2CYP3A4LMNATYR
SCHEMBL8069687 0.81 ESR1 (0.68) ESR1ESR2CYP3A4LMNATYR
SCHEMBL22335854 0.81 ESR1 (0.80) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL9774987 0.81 ESR1 (1.00) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL8058731 0.81 ESR1 (1.00) ESR1ESR2CYP3A4LMNATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4996270-A Unsatured end groups on epoxy resins; heat resistance, toughness BASF AKTIENGESELLSCHAFT (DE) 1991-02-26 US claimed
EP-0207297-B1 VINYL ESTER RESINS BASF Aktiengesellschaft (DE) 1989-01-04 EP claimed
EP-0207297-A1 Vinyl ester resins BASF Aktiengesellschaft (DE) 1987-01-07 EP claimed
US-4269952-A Preparation of glycidyl polyarylethers RHONE-POULENC INDUSTRIES (FR) 1981-05-26 US claimed
US-5214100-A Friedel-crafts alkylation of phenol with chloroprene manufacture by-products BAYER AKTIENGESELLSCHAFT (DE) 1993-05-25 US disclosed
US-4996270-A Unsatured end groups on epoxy resins; heat resistance, toughness BASF AKTIENGESELLSCHAFT (DE) 1991-02-26 US disclosed
EP-0207297-B1 VINYL ESTER RESINS BASF Aktiengesellschaft (DE) 1989-01-04 EP disclosed
EP-0207297-A1 Vinyl ester resins BASF Aktiengesellschaft (DE) 1987-01-07 EP disclosed
US-4383118-A Preparation of glycidyl polyethers of polyphenols RHONE-POULENC INDUSTRIES (FR) 1983-05-10 US disclosed
US-4273915-A TRIS/OXYALKYL/AMINE, APROTIC SOLVENT, EPOXY RESIN RHONE-POULENC INDUSTRIES (FR) 1981-06-16 US disclosed
US-4269952-A Preparation of glycidyl polyarylethers RHONE-POULENC INDUSTRIES (FR) 1981-05-26 US disclosed
US-4246038-A ANHYDRIDE-HYDROXYPROPYLTRIETHOXYSILANE REACTION PRODUCT GENERAL ELECTRIC COMPANY (US) 1981-01-20 US disclosed