Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826102 | 0.85 | KEAP1 (0.46) | KEAP1OPRL1IL23R | |
| SCHEMBL29759478 | 0.83 | KEAP1 (0.40) | KEAP1OPRL1 | |
| SCHEMBL26426461 | 0.81 | KEAP1 (0.40) | KEAP1FOLH1 | |
| SCHEMBL29826494 | 0.80 | FOLH1 (0.47) | KEAP1OPRL1FOLH1NOD1 | |
| SCHEMBL13254722 | 0.77 | IL23R (0.54) | IL23R | |
| SCHEMBL13209217 | 0.77 | IL23R (0.61) | IL23R | |
| SCHEMBL22342398 | 0.77 | TLR2 (0.47) | KEAP1FOLH1NOD1 | |
| SCHEMBL29826021 | 0.76 | SLC6A5 (0.45) | OPRL1FOLH1 | |
| SCHEMBL15358627 | 0.76 | TLR2 (0.40) | — | |
| SCHEMBL27915864 | 0.75 | OPRL1 (0.54) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100196282-A1 | OPTICAL IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100196282-A1 | OPTICAL IMAGING AGENTS | VIP, SSTR4, NGLY1 | KEAP1 1613/4885OPRL1 585/4885FOLH1 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.