SCHEMBL13228930

SCHEMBL13228930

COC(=O)c1c(-c2ccccc2)ccc(-c2ccccc2)c1C(=O)OC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.62
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
LMNA P02545 3/20 0.60
ALDH1A1 P00352 3/20 0.60
HPGD P15428 1/20 0.60
PRKCZ Q05513 1/20 0.60
GABRA1 P14867 2/20 0.58
GABRG2 P18507 2/20 0.58
GABRB3 P28472 2/20 0.58
GABRA3 P34903 2/20 0.58
GABRA5 P31644 1/20 0.58
EGFR P00533 1/20 0.56
TSHR P16473 1/20 0.54
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11152302 0.91 HTT (0.54) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL17264239 0.91 CA12 (0.58) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL25550061 0.89 HTT (0.59) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL29416802 0.87 HTT (0.54) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL28769108 0.87 HTT (0.50) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL8913632 0.84 HTT (0.51) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL16810203 0.84 NCEH1 (0.55) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL4827133 0.83 HTT (0.58) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL69682 0.83 SLC6A3 (0.57) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL9049651 0.83 CA12 (0.69) HTTMEN1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022144899-A1 CHEMICALLY STABLE ION CONDUCTORS AND USES THEREOF TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2022-07-07 WO disclosed
US-7754841-B2 Polymer MERCK PATENT GMBH (DE) 2010-07-13 US disclosed
US-7754841-B2 Polymer MERCK PATENT GMBH (DE) 2010-07-13 US disclosed
EP-1639027-B1 POLYMERS MERCK PATENT GMBH (DE) 2009-04-01 EP disclosed