Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13228930 | 0.91 | HTT (0.62) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3686832 | 0.87 | LMNA (0.53) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL69682 | 0.86 | SLC6A3 (0.57) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3576573 | 0.85 | MEN1 (0.58) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11311111 | 0.83 | CA12 (0.48) | ALDH1A1HPGDGABRG2GABRB3GABRA3 | |
| SCHEMBL17264239 | 0.83 | CA12 (0.58) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6490325 | 0.82 | GABRA1 (0.48) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4576984 | 0.82 | HTT (0.47) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL31636317 | 0.81 | SLC6A3 (0.55) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29057957 | 0.81 | SLC6A3 (0.55) | HTTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4411949-A | FIRE RESISTANT POLYURETHANES | THE CELOTEX CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |