Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | DDO | Q99489 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193247 | 1.00 | TRPM4 (0.41) | TRPM4DAOALDH1A1HPGDKDM4E | |
| SCHEMBL11645830 | 0.83 | TRPM4 (0.39) | TRPM4DAOALDH1A1HPGDKDM4E | |
| SCHEMBL22159773 | 0.81 | TRPM4 (0.38) | TRPM4DAOALDH1A1HPGDKDM4E | |
| SCHEMBL22159978 | 0.81 | TRPM4 (0.38) | TRPM4DAOALDH1A1HPGDKDM4E | |
| SCHEMBL4802146 | 0.80 | KDM4E (0.44) | TRPM4DAOALDH1A1HPGDKDM4E | |
| SCHEMBL22981765 | 0.78 | TRPM4 (0.39) | TRPM4DAOALDH1A1HPGDKDM4E | |
| SCHEMBL11764397 | 0.78 | IDO1 (0.38) | TRPM4ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL11247416 | 0.78 | TRPM4 (0.39) | TRPM4DAOALDH1A1HPGDKDM4E | |
| SCHEMBL11764391 | 0.78 | TRPM4 (0.39) | TRPM4DAOALDH1A1HPGDKDM4E | |
| SCHEMBL1717201 | 0.78 | BRD4 (0.37) | DAOALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648954-B1 | MICROPOROUS POLYMER MATERIAL | UNIV MANCHESTER (GB) | 2014-11-05 | — | — | EP | disclosed |
| US-8056732-B2 | Microporous polymer material | THE UNIVERSITY OF MANCHESTER (GB) | 2011-11-15 | — | — | US | disclosed |
| EP-2267061-A1 | Microporous polymer material | The University Of Manchester (GB) | 2010-12-29 | — | — | EP | disclosed |
| US-20100304112-A1 | MICROPOROUS POLYMER MATERIAL | THE UNIVERSITY OF MANCHESTER (GB) | 2010-12-02 | — | — | US | disclosed |
| WO-2010048694-A1 | LADDER POLYMERS WITH INTRINSIC MICROPOROSITY AND PROCESS FOR PRODUCTION THEREOF | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2010-05-06 | — | — | WO | disclosed |
| US-7690514-B2 | Microporous polymer material | THE UNIVERSITY OF MANCHESTER (GB) | 2010-04-06 | — | — | US | disclosed |
| US-20060246273-A1 | Microporous polymer material | MANCHESTER, UNIVERSITY OF, THE (GB) | 2006-11-02 | — | — | US | disclosed |
| EP-1648954-A2 | MICROPOROUS POLYMER MATERIAL | The University of Manchester (GB) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005012397-A2 | MICROPOROUS POLYMER MATERIAL | THE UNIVERSITY OF MANCHESTER (GB) | 2005-02-10 | — | — | WO | disclosed |