Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PLG | P00747 | 2/20 | 0.32 |
| ▸ | KLK1 | P06870 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193247 | 0.78 | TRPM4 (0.41) | ALOX15POLBSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL1322927 | 0.78 | TRPM4 (0.41) | ALOX15POLBSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL731428 | 0.78 | IDO1 (0.36) | IDO1ALOX15TSHRPOLBSMN1; SMN2 | |
| SCHEMBL76620 | 0.75 | IDO1 (0.34) | IDO1ALOX15TSHRPOLBSMN1; SMN2 | |
| SCHEMBL1717201 | 0.75 | BRD4 (0.37) | ALOX15ALDH1A1HSD17B10HPGDCYP1A2 | |
| SCHEMBL11764391 | 0.75 | TRPM4 (0.39) | ALOX15TSHRPDPK1ALDH1A1HSD17B10 | |
| SCHEMBL6942856 | 0.72 | BACE1 (0.45) | ALDH1A1HSD17B10HPGDMEN1MAPT | |
| SCHEMBL10670045 | 0.72 | BACE1 (0.45) | ALDH1A1HSD17B10HPGDMEN1MAPT | |
| SCHEMBL11800563 | 0.72 | IDO1 (0.37) | IDO1ALOX15TSHRPOLBSMN1; SMN2 | |
| SCHEMBL24252 | 0.71 | CYP2A6 (0.41) | ALOX15TSHRPDPK1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033945-A | Water-soluble trisazo 8-amino-naphthol-1 dyes | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | claimed |
| US-4033945-A | Water-soluble trisazo 8-amino-naphthol-1 dyes | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | disclosed |