Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 4/20 | 0.40 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | DDO | Q99489 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193247 | 0.80 | TRPM4 (0.41) | KDM4EGAAHPGDALDH1A1STAT3 | |
| SCHEMBL64492 | 0.80 | BRD4 (0.39) | HPGDALDH1A1NQO2CYP1A2TDP1 | |
| SCHEMBL1322927 | 0.80 | TRPM4 (0.41) | KDM4EGAAHPGDALDH1A1STAT3 | |
| SCHEMBL3269198 | 0.77 | ACHE (0.34) | CYP1A2TDP1CYP2A6 | |
| SCHEMBL11247416 | 0.77 | TRPM4 (0.39) | KDM4EGAAHPGDALDH1A1STAT3 | |
| SCHEMBL11764391 | 0.77 | TRPM4 (0.39) | KDM4EGAAHPGDALDH1A1STAT3 | |
| SCHEMBL10822591 | 0.77 | MAPT (0.35) | ALDH1A1CYP1A2TDP1LMNACYP2A6 | |
| SCHEMBL76620 | 0.77 | IDO1 (0.34) | HPGDALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL22981765 | 0.77 | TRPM4 (0.39) | KDM4EGAAHPGDALDH1A1STAT3 | |
| SCHEMBL1717201 | 0.77 | BRD4 (0.37) | KDM4EGAAHPGDALDH1A1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7433118-B2 | Bridged polysesquioxane host matrices containing lanthanides chelated by organic guest ligands, and methods of making such matrices | LUCENT TECHNOLOGIES INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-20040263952-A1 | Bridged polysesquioxane host matrices containing lanthanides chelated by organic guest ligands, and methods of making such matrices | LUCENT TECHNOLOGIES, INC. (US) | 2004-12-30 | — | — | US | disclosed |