SCHEMBL13235486

SCHEMBL13235486

CCOc1ccc(-c2ccc(-c3ccc(CC)cc3)cc2)c(F)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGFR2 P21802 2/20 0.36
▸ FGFR1 P11362 1/20 0.36
▸ RXRA P19793 1/20 0.36
▸ RXRB P28702 1/20 0.36
▸ RXRG P48443 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ POLB P06746 2/20 0.35
▸ MAPT P10636 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ LMNA P02545 1/20 0.35
▸ XBP1 P17861 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ FFAR4 Q5NUL3 1/20 0.35
▸ S1PR1 P21453 2/20 0.34
▸ S1PR3 Q99500 2/20 0.34
▸ FAAH O00519 1/20 0.33
▸ ESR1 P03372 1/20 0.33
▸ GRM2 Q14416 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2877758 0.89 FFAR4 (0.38) FGFR2FGFR1RXRARXRBRXRG
SCHEMBL16871137 0.88 FGFR2 (0.39) FGFR2FGFR1RXRARXRBRXRG
SCHEMBL13235489 0.87 SMN1; SMN2 (0.40) HPGDS1PR1MEN1KMT2AHSD17B10
SCHEMBL13235470 0.87 CYP17A1 (0.38) FAAHPTGS2CYP3A4
SCHEMBL14311214 0.87 ADORA3 (0.39) FGFR2FGFR1ALDH1A1POLBMAPT
SCHEMBL10091331 0.86 FGFR2 (0.40) FGFR2FGFR1RXRARXRBRXRG
SCHEMBL13235477 0.85 RARB (0.43) ALDH1A1MAPTHPGDLMNAFFAR4
SCHEMBL22902900 0.84 FGFR2 (0.42) FGFR2FGFR1RXRARXRBRXRG
SCHEMBL13754791 0.83 GABRA1 (0.37) FGFR2FGFR1RXRARXRBRXRG
SCHEMBL13235488 0.82 FFAR4 (0.35) FGFR2FGFR1RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758931-B2 Chlorofluorobenzene liquid crystal compound, liquid crystal composition, and liquid crystal display device CHISSO CORPORATION (JP) 2010-07-20 — — US disclosed
US-20090264683-A1 CHLOROFLUOROBENZENE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 2009-10-22 — — US disclosed
US-7569258-B2 Chlorofluorobenzene liquid crystal compound, liquid crystal composition, and liquid crystal display device CHISSO CORPORATION (JP) 2009-08-04 — — US disclosed
US-7569258-B2 Chlorofluorobenzene liquid crystal compound, liquid crystal composition, and liquid crystal display device CHISSO CORPORATION (JP) 2009-08-04 — — US disclosed
EP-1873134-A1 CHLOROFLUOROBENZENE LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2008-01-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264683-A1 CHLOROFLUOROBENZENE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE CCND3, CCND1, SLFN12 FGFR2 701/4885FGFR1 623/4885RXRA 277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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