Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 14/20 | 0.70 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342485 | 0.82 | PDE7A (0.64) | PDE7APDE7BALDH1A1KMT2ALMNA | |
| SCHEMBL17985425 | 0.82 | PDE7A (0.55) | PDE7APDE7BALDH1A1KMT2ALMNA | |
| SCHEMBL28405 | 0.80 | PDE7A (0.77) | PDE7APDE7BALDH1A1KMT2ALMNA | |
| SCHEMBL4963975 | 0.76 | PDE7A (0.82) | PDE7APDE7BALDH1A1KMT2ALMNA | |
| SCHEMBL5880619 | 0.76 | PDE7A (0.69) | PDE7APDE7BKMT2AMAPK1TSHR | |
| SCHEMBL27735806 | 0.74 | MAPK1 (0.51) | PDE7APDE7BALDH1A1KMT2ALMNA | |
| SCHEMBL2960424 | 0.73 | SLC6A4 (0.61) | PDE7APDE7BALDH1A1KMT2ALMNA | |
| SCHEMBL29485896 | 0.73 | MAPK1 (0.64) | PDE7APDE7BALDH1A1KMT2ALMNA | |
| SCHEMBL29348 | 0.73 | MAPK1 (0.64) | PDE7APDE7BALDH1A1KMT2ALMNA | |
| SCHEMBL13236393 | 0.73 | PDE7A (0.57) | PDE7APDE7BALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7750158-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| US-7750158-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |