Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 12/20 | 0.82 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22815433 | 0.91 | PDE7A (0.74) | PDE7APDE7BPDE4BPDE4DKMT2A | |
| SCHEMBL28405 | 0.90 | PDE7A (0.77) | PDE7APDE7BPDE4BPDE4DKMT2A | |
| SCHEMBL10249311 | 0.87 | PDE7A (1.00) | PDE7APDE7BPDE4BPDE4DKMT2A | |
| SCHEMBL8098834 | 0.84 | PDE7A (0.64) | PDE7APDE7BPDE4BPDE4DKMT2A | |
| SCHEMBL7665295 | 0.83 | PDE7A (0.67) | PDE7APDE7BPDE4BPDE4DKMT2A | |
| SCHEMBL9537682 | 0.82 | MAPT (0.60) | PDE7APDE7BPDE4BPDE4DKMT2A | |
| SCHEMBL2962041 | 0.82 | PDE7A (0.65) | PDE7APDE7BPDE4BPDE4DKMT2A | |
| SCHEMBL20535456 | 0.81 | PDE7A (0.65) | PDE7APDE7BPDE4BPDE4DKMT2A | |
| SCHEMBL27561251 | 0.79 | TXNRD1 (0.70) | PDE7APDE7BPDE4BPDE4DTDP1 | |
| SCHEMBL2545546 | 0.79 | MAPK1 (0.58) | PDE7APDE7BPDE4BPDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890547-A2 | CONTROL OF PARASITES IN ANIMALS BY N-[(PHENYLOXY)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE AND N-[(PHENYLSULFANYL)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE DERIVATIVES | Schering-Plough Ltd. (CH) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006135648-A2 | CONTROL OF PARASITES IN ANIMALS BY N-[(PHENYLOXY)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE AND N-[(PHENYLSULFANYL)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE DERIVATIVES | SCHERING-PLOUGH LTD. (CH) | 2006-12-21 | — | — | WO | disclosed |
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | ELANE, CTRL, PIGO | PDE7A 2394/4885PDE7B 3069/4885PDE4B 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.