SCHEMBL13237669

SCHEMBL13237669

CC(CC1CC2C=CC1C2)NS(=O)(=O)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 1/20 0.33
PKM P14618 1/20 0.31
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4872914 0.77 KDM4E (0.30) KDM4E
SCHEMBL15133707 0.75 KDM4E (0.35) KDM4EALDH1A1PKMMEN1CYP1A2
SCHEMBL775569 0.75 KDM4E (0.35) KDM4EALDH1A1PKMMEN1CYP1A2
SCHEMBL15492261 0.73 KDM4E (0.34) KDM4EALDH1A1MEN1CYP1A2CYP3A4
SCHEMBL17120353 0.72 KDM4E (0.36) KDM4EALDH1A1PKMMEN1CYP1A2
SCHEMBL775863 0.72 EPHX1 (0.36) KDM4EALDH1A1PKMMEN1CYP1A2
SCHEMBL13532352 0.72 KDM4E (0.40) KDM4EALDH1A1MEN1CYP1A2CYP3A4
SCHEMBL465320 0.71 KDM4E (0.47) KDM4EALDH1A1MEN1CYP1A2CYP3A4
SCHEMBL8531194 0.70 EPHX1 (0.41) KDM4EALDH1A1PKMMEN1CYP1A2
SCHEMBL1142701 0.70 KDM4E (0.36) KDM4EALDH1A1PKMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8753790-B2 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS, LLC (US) 2014-06-17 US disclosed
US-8748074-B2 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS, LLC (US) 2014-06-10 US disclosed
US-8329838-B2 Norbornene-type polymers, compositions thereof and lithographic processes using such compositions PROMERUS LLC (US) 2012-12-11 US disclosed
US-20120129101-A1 Self-Imageable Film Forming Polymer, Compositions Thereof and Devices and Structures Made Therefrom PROMERUS LLC (US) 2012-05-24 US disclosed
US-20110104614-A1 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS LLC 2011-05-05 US disclosed
US-20110065878-A1 Norbornene-Type Polymers, Compositions Thereof And Lithographic Processes Using Such Compositions PROMERUS LLC (US) 2011-03-17 US disclosed
US-20110009578-A1 Use Of A Combination Chain Transfer And Activating Agent To Control Molecular Weight And Optical Density Of Pd Catalyzed Norbornene Polymers PROMERUS LLC (US) 2011-01-13 US disclosed
US-7759439-B2 Use of a combination chain transfer and activating agent to control molecular weight and optical density of Pd catalyzed norbornene polymers PROMERUS LLC (US) 2010-07-20 US disclosed
US-7759439-B2 Use of a combination chain transfer and activating agent to control molecular weight and optical density of Pd catalyzed norbornene polymers PROMERUS LLC (US) 2010-07-20 US disclosed
US-20080242810-A1 Use of a Combination Chain Transfer and Activating Agent to Control Molecular Weight and Optical Density of Pd Catalyzed Norbornene Polymers PROMERUS LLC (US) 2008-10-02 US disclosed
US-20080242810-A1 Use of a Combination Chain Transfer and Activating Agent to Control Molecular Weight and Optical Density of Pd Catalyzed Norbornene Polymers PROMERUS LLC (US) 2008-10-02 US disclosed