SCHEMBL775569

SCHEMBL775569

O=S(=O)(NCC1CC2C=CC1C2)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.35
ALDH1A1 P00352 2/20 0.34
PKM P14618 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 2/20 0.31
EPHX1 P07099 1/20 0.31
TSHR P16473 1/20 0.31
CA2 P00918 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2632934 0.91 KDM4E (0.34) KDM4EALDH1A1PKMMEN1CYP1A2
SCHEMBL2632935 0.85 CA1 (0.34) KDM4EALDH1A1PKMMEN1CYP1A2
SCHEMBL775863 0.84 EPHX1 (0.36) KDM4EALDH1A1PKMMEN1CYP1A2
SCHEMBL8531194 0.82 EPHX1 (0.41) KDM4EALDH1A1PKMMEN1CYP1A2
SCHEMBL13595432 0.79 KDM4E (0.36) KDM4EALDH1A1PKMTDP1LMNA
SCHEMBL3645416 0.78 KDM4E (0.40) KDM4EALDH1A1PKMTDP1LMNA
SCHEMBL3649759 0.78 KDM4E (0.40) KDM4EALDH1A1PKMTDP1LMNA
SCHEMBL6935344 0.78 KDM4E (0.43) KDM4EALDH1A1PKMMEN1KMT2A
SCHEMBL6355414 0.77 KDM4E (0.42) KDM4EALDH1A1PKMMEN1KMT2A
SCHEMBL13237669 0.75 KDM4E (0.34) KDM4EALDH1A1PKMMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10591818-B2 Nadic anhydride polymers and photosensitive compositions derived therefrom PROMERUS, LLC (US) 2020-03-17 US claimed
US-20180030189-A1 NADIC ANHYDRIDE POLYMERS AND PHOTOSENSITIVE COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-02-01 US claimed
US-8753790-B2 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS, LLC (US) 2014-06-17 US claimed
US-7550630-B2 Process for producing N-(bicyclo[2.2.1]hept-5-en-2-ylmethyl)-1,1,1-trifluoromethanesulfonamide CENTRAL GLASS COMPANY, LIMITED (JP) 2009-06-23 US claimed
US-20080071113-A1 Process for producing n-(bicyclo[2.2.1]hept-5-en-2-ylmethyl)-1,1,1-trifluoromethanesulfonamide CENTRAL GLASS COMPANY, LIMITED (JP) 2008-03-20 US claimed
US-10591818-B2 Nadic anhydride polymers and photosensitive compositions derived therefrom PROMERUS, LLC (US) 2020-03-17 US disclosed
WO-2018022952-A1 NADIC ANHYDRIDE POLYMERS AND PHOTOSENSITIVE COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-02-01 WO disclosed
WO-2018022952-A1 NADIC ANHYDRIDE POLYMERS AND PHOTOSENSITIVE COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-02-01 WO disclosed
US-20180030189-A1 NADIC ANHYDRIDE POLYMERS AND PHOTOSENSITIVE COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-02-01 US disclosed
US-20180030189-A1 NADIC ANHYDRIDE POLYMERS AND PHOTOSENSITIVE COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-02-01 US disclosed
US-9671693-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-06 US disclosed
US-9671693-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-06 US disclosed
US-7189490-B2 Photoresists containing sulfonamide component SHIPLEY COMPANY, L.L.C. (US) 2007-03-13 US disclosed
US-7189490-B2 Photoresists containing sulfonamide component SHIPLEY COMPANY, L.L.C. (US) 2007-03-13 US disclosed
EP-1157058-B1 METHOD OF PREPARING NORBORNENE SULFONAMIDE POLYMERS SUMITOMO BAKELITE CO (JP) 2003-06-25 EP disclosed
US-6420503-B1 POLYCARBONS/OTHER/ SUMITOMO BAKELITE CO. LTD. (JP) 2002-07-16 US disclosed
EP-1157058-A1 METHOD OF PREPARING NORBORNENE SULFONAMIDE POLYMERS The B.F. Goodrich Company (US) 2001-11-28 EP disclosed
US-6235849-B1 INCLUDE COPOLYMERS WITH ONE OR MORE COMONOMERS SUCH AS NORBORNENE, ETHYLENE, AN ACRYLATE OR SULFUR DIOXIDE OR CARBON MONOXIDE; ALSO RING-OPENING METATHESIS POLYMERIZATION; GROUP VIII METAL COMPOUND CATALYST THE B. F. GOODRICH COMPANY 2001-05-22 US disclosed
WO-2000046267-A1 METHOD OF PREPARING NORBORNENE SULFONAMIDE POLYMERS THE B.F. GOODRICH COMPANY (US) 2000-08-10 WO disclosed
WO-2000046268-A1 NORBORNENE SULFONAMIDE POLYMERS THE B.F. GOODRICH COMPANY (US) 2000-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080071113-A1 Process for producing n-(bicyclo[2.2.1]hept-5-en-2-ylmethyl)-1,1,1-trifluoromethanesulfonamide HCN1, HCN2, KCNMA1 KDM4E 944/4885ALDH1A1 805/4885PKM 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.