Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 17/20 | 0.38 |
| ▸ | OXTR | P30559 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2961930 | 0.92 | LMNA (0.40) | LMNASMN1; SMN2AVPR2OXTRAVPR1A | |
| SCHEMBL13239413 | 0.92 | LMNA (0.40) | LMNASMN1; SMN2AVPR2OXTRAVPR1A | |
| SCHEMBL13239411 | 0.86 | RECQL (0.42) | LMNASMN1; SMN2AVPR2 | |
| SCHEMBL2957677 | 0.81 | AVPR2 (0.40) | LMNASMN1; SMN2AVPR2OXTRAVPR1A | |
| SCHEMBL2957847 | 0.81 | MMP1 (0.42) | LMNASMN1; SMN2AVPR2AVPR1A | |
| SCHEMBL2961925 | 0.81 | HSD17B3 (0.40) | LMNASMN1; SMN2AVPR2AVPR1AHSD17B3 | |
| SCHEMBL13239401 | 0.81 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL2960734 | 0.81 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL2960127 | 0.79 | AVPR2 (0.42) | AVPR2OXTRAVPR1AHSD17B3 | |
| SCHEMBL2951584 | 0.79 | AVPR2 (0.41) | AVPR2OXTRAVPR1AHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763605-B2 | [1,4]benzodiazepines as vasopressin V2 receptor antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2010-07-27 | — | — | US | disclosed |