Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450658 | 0.89 | ESR1 (0.42) | ESR1ESR2SHBGMAPT | |
| SCHEMBL2043301 | 0.87 | ESR2 (0.49) | ESR1ESR2FYNSHBGOPRM1 | |
| SCHEMBL20763440 | 0.86 | ESR2 (0.43) | ESR1ESR2FYNSHBGOPRK1 | |
| SCHEMBL6056612 | 0.85 | FYN (0.36) | ESR1ESR2FYNSHBG | |
| SCHEMBL10459748 | 0.85 | ESR2 (0.50) | ESR1ESR2FYNOPRM1OPRK1 | |
| SCHEMBL1323965 | 0.85 | ESR1 (0.47) | ESR1ESR2FYNOPRM1OPRK1 | |
| SCHEMBL8021816 | 0.82 | ESR2 (0.50) | ESR1ESR2FYNSHBGOPRM1 | |
| SCHEMBL9354044 | 0.80 | ESR2 (0.47) | ESR1ESR2FYNOPRM1OPRK1 | |
| SCHEMBL9354045 | 0.80 | ESR2 (0.47) | ESR1ESR2FYNOPRM1OPRK1 | |
| SCHEMBL6453710 | 0.78 | ESR1 (0.54) | ESR1ESR2FYNMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148570-A1 | Novel substituted alkane compounds and uses thereof | HUANG LIREN (US) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148570-A1 | Novel substituted alkane compounds and uses thereof | ALK, CYP11B2, ALKBH2 | ESR1 1005/4885ESR2 293/4885FYN 2670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.