Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.48 |
| ▸ | ESR1 | P03372 | 8/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1323965 | 0.81 | ESR1 (0.47) | ESR2ESR1CYP3A4ARTSHR | |
| SCHEMBL6455713 | 0.78 | ESR1 (0.58) | ESR2ESR1ARLMNA | |
| SCHEMBL6453699 | 0.78 | ESR1 (0.45) | ESR2ESR1SHBGOPRM1OPRK1 | |
| SCHEMBL6056663 | 0.77 | ESR1 (0.38) | ESR2ESR1TSHRSLC6A4SLC6A3 | |
| SCHEMBL6451587 | 0.77 | ESR1 (0.47) | ESR2ESR1CYP3A4ARHPGD | |
| SCHEMBL6450658 | 0.75 | ESR1 (0.42) | ESR2ESR1CYP3A4HPGDSLC6A2 | |
| SCHEMBL9065610 | 0.75 | ESR1 (0.40) | ESR2ESR1CYP3A4ARHPGD | |
| SCHEMBL8959239 | 0.74 | ESR1 (0.45) | ESR2ESR1CYP3A4ARHPGD | |
| SCHEMBL544625 | 0.74 | ESR2 (0.72) | ESR2ESR1CYP3A4ARHPGD | |
| SCHEMBL9437447 | 0.73 | ESR2 (0.56) | ESR2ESR1CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148570-A1 | Novel substituted alkane compounds and uses thereof | HUANG LIREN (US) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148570-A1 | Novel substituted alkane compounds and uses thereof | ALK, CYP11B2, ALKBH2 | ESR2 293/4885ESR1 1005/4885CYP3A4 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.