Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27856456 | 0.81 | TSHR (0.64) | ALDH1A1TSHR | |
| SCHEMBL602476 | 0.81 | TSHR (0.64) | ALDH1A1TSHR | |
| SCHEMBL27498001 | 0.81 | TSHR (0.45) | ALDH1A1TSHR | |
| SCHEMBL4579700 | 0.79 | TSHR (0.68) | ALDH1A1TSHR | |
| SCHEMBL10835138 | 0.78 | TSHR (0.60) | ALDH1A1TSHR | |
| SCHEMBL16884943 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL13219150 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL13219149 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHR | |
| SCHEMBL4826914 | 0.76 | ALDH1A1 (0.75) | ALDH1A1TSHR | |
| SCHEMBL29445 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10196471-B1 | Curable composition having an electron deficient olefin | Henkel IP & Holding GmbH (DE) | 2019-02-05 | — | — | US | disclosed |
| EP-2217559-B1 | ELECTRON DEFICIENT OLEFINS | Henkel IP & Holding GmbH (DE) | 2017-06-28 | — | — | EP | disclosed |
| US-9481640-B2 | Electron deficient olefins | Henkel IP & Holding GmbH (DE) | 2016-11-01 | — | — | US | disclosed |
| US-20150191424-A1 | ELECTRON DEFICIENT OLEFINS | Henkel IP & Holding GmbH (DE) | 2015-07-09 | — | — | US | disclosed |
| US-20100210788-A1 | ELECTRON DEFICIENT OLEFINS | LOCTITE (R&D) LIMITED (IE) | 2010-08-19 | — | — | US | disclosed |
| WO-2009053484-A2 | ELECTRON DEFICIENT OLEFINS AND CURABLE COMPOSITIONS PREPARED THEREFROM | LOCTITE (R & D) LIMITED (IE) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210788-A1 | ELECTRON DEFICIENT OLEFINS | MAL2, IDH2, SLC25A11 | ALDH1A1 838/4885TSHR 4873/4885 |
| US-20150191424-A1 | ELECTRON DEFICIENT OLEFINS | MAL2, IDH2, SLC25A11 | ALDH1A1 838/4885TSHR 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.