SCHEMBL4579700

SCHEMBL4579700

C=C(C#N)C(=O)OCCOC(=O)C(=C)C#N

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.68
ALDH1A1 P00352 3/20 0.68
THRB P10828 1/20 0.39
DNM1 Q05193 3/20 0.35
CYP2C9 P11712 1/20 0.31
TP53 P04637 2/20 0.30
HIF1A Q16665 2/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16290353 0.93 TSHR (0.61) TSHRALDH1A1THRBDNM1TP53
SCHEMBL3786036 0.93 TSHR (0.61) TSHRALDH1A1THRBDNM1TP53
SCHEMBL3791084 0.93 TSHR (0.61) TSHRALDH1A1THRBDNM1TP53
SCHEMBL4580407 0.91 TSHR (0.63) TSHRALDH1A1THRBDNM1
SCHEMBL4578754 0.91 TSHR (0.63) TSHRALDH1A1THRBDNM1
SCHEMBL487323 0.89 TSHR (0.62) TSHRALDH1A1THRBDNM1CYP2C9
SCHEMBL20706516 0.89 TSHR (0.62) TSHRALDH1A1THRBDNM1CYP2C9
SCHEMBL8371105 0.89 ALDH1A1 (0.62) TSHRALDH1A1THRBDNM1HSD17B10
SCHEMBL1982870 0.89 TSHR (0.61) TSHRALDH1A1THRBDNM1
SCHEMBL1982599 0.89 TSHR (0.61) TSHRALDH1A1THRBDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4194523-A1 CYANOACRYLATE ADHESIVE COMPOSITION Cuantum Medical Cosmetics, S.L. (ES) 2023-06-14 EP claimed
CN-121930411-A Gel electrolyte precursor, gel electrolyte and lithium ion battery 宁德国泰华荣新材料有限公司 2026-04-28 CN disclosed
EP-4194523-A1 CYANOACRYLATE ADHESIVE COMPOSITION Cuantum Medical Cosmetics, S.L. (ES) 2023-06-14 EP disclosed
US-7341716-B2 Occlusive composition BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-03-11 US disclosed
EP-1494999-B1 OCCLUSIVE COMPOSITION COMPRISING A POLY(2-CYANOACRYLATE) MONOMER BOSTON SCIENT LTD (BB) 2006-06-07 EP disclosed
EP-1494999-A1 OCCLUSIVE COMPOSITION COMPRISING A POLY(2-CYANOACRYLATE) MONOMER Boston Scientific Limited (BB) 2005-01-12 EP disclosed
WO-2003087042-A1 OCCLUSIVE COMPOSITION COMPRISING A POLY (2-CYANOACRYLATE) MONOMER BOSTON SCIENTIFIC LIMITED (BB) 2003-10-23 WO disclosed
US-20030194389-A1 Occlusive composition STRYKER CORPORATION 2003-10-16 US disclosed
EP-0686681-B1 Alpha-cyanoacrylate adhesive composition TAOKA CHEMICAL CO LTD (JP) 1998-08-05 EP disclosed
EP-0690112-A1 Cyanoacrylate adhesive compositions TAOKA CHEMICAL COMPANY, LIMITED (JP) 1996-01-03 EP disclosed
EP-0686681-A1 Alpha-cyanoacrylate adhesive composition TAOKA CHEMICAL COMPANY, LIMITED (JP) 1995-12-13 EP disclosed
EP-0063037-B1 ADHESIVE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-25 EP disclosed
US-4377490-A CYANOACRYLATE, ETHERS, ALCOHOLS, ACIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-03-22 US disclosed
EP-0063037-A2 Adhesive composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-10-20 EP disclosed
US-4041062-A CROSSLINKING AGENTS FOR DENTAL ADHESIVE, SEALING OR COATING POLYMERS JOHNSON & JOHNSON (US) 1977-08-09 US disclosed
US-4041063-A CROSSLINKING AGENTS FOR DENTAL ADHESIVE, SEALING OR COATING POLYMERS JOHNSON & JOHNSON (US) 1977-08-09 US disclosed
US-4041061-A CROSSLINKING AGENTS FOR DENTAL ADHESIVE, SEALING OR COATING POLYMERS JOHNSON & JOHNSON (US) 1977-08-09 US disclosed
US-4013703-A CROSSLINKING AGENTS; MONOMERS FOR ADHESIVE POLYMERS JOHNSON & JOHNSON (US) 1977-03-22 US disclosed
US-4003942-A CROSSLINKING AGENTS; DENTAL ADHESIVES JOHNSON & JOHNSON (US) 1977-01-18 US disclosed
US-3975422-A Preparation of bis (2-cyanoacrylate)monomers JOHNSON & JOHNSON (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030194389-A1 Occlusive composition C3AR1, F12, FGB TSHR 3434/4885ALDH1A1 1135/4885THRB 3827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.