Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 12/20 | 0.59 |
| ▸ | F13A1 | P00488 | 9/20 | 0.59 |
| ▸ | TGM1 | P22735 | 6/20 | 0.59 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.59 |
| ▸ | STS | P08842 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3248533 | 0.95 | TGM2 (0.55) | TGM2F13A1TGM1TGM3STS | |
| SCHEMBL28919020 | 0.86 | STS (0.63) | TGM2F13A1TGM1TGM3STS | |
| SCHEMBL5262401 | 0.85 | TGM2 (0.51) | TGM2F13A1TGM1TGM3GPR119 | |
| SCHEMBL1180627 | 0.85 | TGM2 (0.60) | TGM2F13A1TGM1TGM3POLB | |
| SCHEMBL29060789 | 0.84 | MAPT (0.73) | TGM2F13A1TGM1TGM3STS | |
| SCHEMBL2252120 | 0.83 | TGM2 (0.63) | TGM2F13A1TGM1GPR119 | |
| SCHEMBL4266289 | 0.83 | CNR1 (0.59) | TGM2F13A1TGM1TGM3MAPT | |
| SCHEMBL20100253 | 0.83 | TGM2 (0.49) | TGM2F13A1TGM1TGM3GPR119 | |
| SCHEMBL5259618 | 0.83 | TGM2 (0.52) | TGM2F13A1TGM1TGM3STS | |
| SCHEMBL18711516 | 0.83 | ALDH1A1 (0.62) | MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759339-B2 | Hydroxysteroid dehydrogenase inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2010-07-20 | — | — | US | disclosed |
| US-7759339-B2 | Hydroxysteroid dehydrogenase inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2010-07-20 | — | — | US | disclosed |