Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPEP1 | P16444 | 10/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13240771 | 1.00 | DPEP1 (1.00) | DPEP1NPC1RAB9ATDP1IDO1 | |
| SCHEMBL13240770 | 0.89 | DPEP1 (1.00) | DPEP1NPC1RAB9AGRIK1 | |
| SCHEMBL13240773 | 0.89 | DPEP1 (1.00) | DPEP1NPC1RAB9AGRIK1 | |
| SCHEMBL13241006 | 0.86 | DPEP1 (1.00) | DPEP1NPC1RAB9AHDAC3HDAC1 | |
| SCHEMBL13241009 | 0.86 | DPEP1 (1.00) | DPEP1NPC1RAB9AHDAC3HDAC1 | |
| SCHEMBL13241007 | 0.86 | DPEP1 (1.00) | DPEP1RAB9AGRIK1 | |
| SCHEMBL13241008 | 0.86 | DPEP1 (1.00) | DPEP1RAB9AGRIK1 | |
| SCHEMBL13240775 | 0.83 | DPEP1 (1.00) | DPEP1GRIK1HPGD | |
| SCHEMBL13241013 | 0.80 | DPEP1 (1.00) | DPEP1 | |
| SCHEMBL13241012 | 0.80 | DPEP1 (1.00) | DPEP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7785564-B2 | an enzyme overexpressed in benign and malignant colon tumors; Aminophosphinic acid derivatives used therapeutically and diagnostically for treatment and detection of tumors | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-08-31 | — | — | US | disclosed |