Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPEP1 | P16444 | 10/20 | 1.00 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13241008 | 1.00 | DPEP1 (1.00) | DPEP1CTSLMETAP1METAP2MC4R | |
| SCHEMBL13241006 | 0.89 | DPEP1 (1.00) | DPEP1METAP1METAP2GRIK1RAB9A | |
| SCHEMBL13241009 | 0.89 | DPEP1 (1.00) | DPEP1METAP1METAP2GRIK1RAB9A | |
| SCHEMBL13240770 | 0.86 | DPEP1 (1.00) | DPEP1METAP1METAP2GRIK1RAB9A | |
| SCHEMBL13240771 | 0.86 | DPEP1 (1.00) | DPEP1GRIK1RAB9A | |
| SCHEMBL13240776 | 0.86 | DPEP1 (1.00) | DPEP1GRIK1RAB9A | |
| SCHEMBL13240773 | 0.86 | DPEP1 (1.00) | DPEP1METAP1METAP2GRIK1RAB9A | |
| SCHEMBL13240774 | 0.85 | DPEP1 (0.74) | DPEP1METAP2POLBRAB9AKMT2A | |
| SCHEMBL13240772 | 0.85 | DPEP1 (0.74) | DPEP1METAP2POLBRAB9AKMT2A | |
| SCHEMBL13240775 | 0.84 | DPEP1 (1.00) | DPEP1METAP1METAP2GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7785564-B2 | an enzyme overexpressed in benign and malignant colon tumors; Aminophosphinic acid derivatives used therapeutically and diagnostically for treatment and detection of tumors | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-08-31 | — | — | US | disclosed |