SCHEMBL13242000

SCHEMBL13242000

Cc1ccc(N(C=C(c2ccccc2)c2ccccc2)c2ccc(/C=C/c3ccc(/C=C/c4ccc(N(C=C(c5ccccc5)c5ccccc5)c5ccc(C)cc5C)cc4)cc3)cc2)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
NFE2L2 Q16236 1/20 0.38
RELA Q04206 1/20 0.37
TRPM8 Q7Z2W7 2/20 0.36
PTGS2 P35354 3/20 0.36
ALOX5 P09917 2/20 0.36
PTGS1 P23219 2/20 0.36
TTR P02766 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.34
INSR P06213 2/20 0.33
SNCA P37840 1/20 0.33
APP P05067 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9972118 0.92 SNCA (0.34) ALDH1A1CYP3A4MAPTHPGDNFE2L2
SCHEMBL9972117 0.91 TTR (0.43) ALDH1A1MAPTHPGDRELAPTGS2
SCHEMBL13580061 0.90 MEN1 (0.34) ALDH1A1CYP3A4MAPTNFE2L2RELA
SCHEMBL13242017 0.89 MAPT (0.34) ALDH1A1MAPTNFE2L2PTGS2ALOX5
SCHEMBL5036465 0.89 MAPT (0.34) ALDH1A1MAPTNFE2L2PTGS2ALOX5
SCHEMBL9972132 0.88 TTR (0.43) ALDH1A1MAPTHPGDRELATRPM8
SCHEMBL4376815 0.88 MAPT (0.36) ALDH1A1MAPTNFE2L2ALOX5CTDSP1
SCHEMBL25071486 0.87 MAPT (0.35) ALDH1A1MAPTNFE2L2PTGS2ALOX5
SCHEMBL16922632 0.87 MAPT (0.33) ALDH1A1MAPTNFE2L2RELAPTGS2
SCHEMBL17735836 0.85 CNR1 (0.35) ALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10203616-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2019-02-12 US disclosed
US-20170285498-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-10-05 US disclosed
US-20170285498-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-10-05 US disclosed
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
US-20100183332-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-07-22 US disclosed
US-20100183332-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-07-22 US disclosed