Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242000 | 0.92 | ALDH1A1 (0.38) | SNCAALOX5PTGS1PTGS2MAPT | |
| SCHEMBL9972117 | 0.88 | TTR (0.43) | ALOX5PTGS1PTGS2MAPTALDH1A1 | |
| SCHEMBL9972132 | 0.86 | TTR (0.43) | ALOX5PTGS1PTGS2MAPTALDH1A1 | |
| SCHEMBL9972122 | 0.83 | SNCA (0.32) | SNCAALOX5PTGS1PTGS2MAPT | |
| SCHEMBL13580061 | 0.83 | MEN1 (0.34) | PTGS2MAPTNFE2L2ALDH1A1CYP3A4 | |
| SCHEMBL5036465 | 0.82 | MAPT (0.34) | ALOX5PTGS2MAPTNFE2L2ALDH1A1 | |
| SCHEMBL13242017 | 0.82 | MAPT (0.34) | ALOX5PTGS2MAPTNFE2L2ALDH1A1 | |
| SCHEMBL9972123 | 0.81 | ALDH1A1 (0.33) | ALOX5PTGS1PTGS2MAPTALDH1A1 | |
| SCHEMBL4376815 | 0.81 | MAPT (0.36) | ALOX5MAPTNFE2L2ALDH1A1LMNA | |
| SCHEMBL25071486 | 0.80 | MAPT (0.35) | ALOX5PTGS2MAPTNFE2L2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120156599-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |