SCHEMBL9972132

SCHEMBL9972132

Cc1cc(C=Cc2ccccc2)ccc1N(C=C(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 4/20 0.43
ALOX5 P09917 2/20 0.43
PTGS1 P23219 2/20 0.43
PTGS2 P35354 2/20 0.43
RELA Q04206 2/20 0.38
APP P05067 1/20 0.36
TUBB1 Q9H4B7 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP1B1 Q16678 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9972117 0.97 TTR (0.43) TTRALOX5PTGS1PTGS2RELA
SCHEMBL13242000 0.88 ALDH1A1 (0.38) TTRALOX5PTGS1PTGS2RELA
SCHEMBL9972123 0.87 ALDH1A1 (0.33) TTRALOX5PTGS1PTGS2RELA
SCHEMBL9972118 0.86 SNCA (0.34) TTRALOX5PTGS1PTGS2RELA
SCHEMBL9972122 0.84 SNCA (0.32) TTRALOX5PTGS1PTGS2RELA
SCHEMBL9972120 0.84 PTGS2 (0.41) PTGS2ALDH1A1LMNAMAPTHPGD
SCHEMBL13580061 0.83 MEN1 (0.34) PTGS2RELAALDH1A1LMNAMAPT
SCHEMBL9972125 0.83 TTR (0.38) TTRALOX5PTGS1PTGS2APP
SCHEMBL9973916 0.83 CYP2A6 (0.36) PTGS2NPC1ALDH1A1LMNAMAPT
SCHEMBL13163966 0.81 RELA (0.48) TTRRELANPC1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120156599-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME SHARP KABUSHIKI KAISHA (JP) 2012-06-21 US disclosed
US-20120156599-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME SHARP KABUSHIKI KAISHA (JP) 2012-06-21 US disclosed