SCHEMBL13242002

SCHEMBL13242002

Cc1cccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(C)c(C)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 4/20 0.42
HSD17B2 P37059 4/20 0.42
MAPT P10636 4/20 0.38
POLB P06746 2/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
EPHX1 P07099 2/20 0.37
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
TSHR P16473 2/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11911545 0.98 HSD17B1 (0.40) HSD17B1HSD17B2MAPTPOLBCTDSP1
SCHEMBL12677671 0.95 HSD17B1 (0.42) HSD17B1HSD17B2ALDH1A1TDP1NPC1
SCHEMBL10706937 0.93 ALDH1A1 (0.41) MAPTALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL18286391 0.92 HSD17B1 (0.40) HSD17B1HSD17B2MAPTALDH1A1TDP1
SCHEMBL17368987 0.92 HSD17B1 (0.47) HSD17B1HSD17B2MAPTPOLBCTDSP1
SCHEMBL13241980 0.92 ALDH1A1 (0.42) HSD17B1HSD17B2MAPTALDH1A1KDM4E
SCHEMBL22422944 0.92 HSD17B1 (0.47) HSD17B1HSD17B2MAPTPOLBCTDSP1
SCHEMBL1263162 0.92 HSD17B1 (0.47) HSD17B1HSD17B2MAPTPOLBCTDSP1
SCHEMBL2500852 0.92 HSD17B1 (0.47) HSD17B1HSD17B2MAPTPOLBCTDSP1
SCHEMBL10065951 0.92 HSD17B1 (0.47) HSD17B1HSD17B2MAPTPOLBCTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7764906-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2010-07-27 US disclosed
US-7764906-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2010-07-27 US disclosed
EP-0977087-B1 Electrophotographic apparatus CANON KK (JP) 2007-12-12 EP disclosed