SCHEMBL13242007

SCHEMBL13242007

COc1ccc(N(C=C(c2ccccc2)c2ccccc2)c2ccc(-c3ccc(N(C=C(c4ccccc4)c4ccccc4)c4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
TSHR P16473 1/20 0.45
KDM4E B2RXH2 2/20 0.42
HPGD P15428 2/20 0.42
ESR2 Q92731 1/20 0.42
MGLL Q99685 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.41
PDE4A P27815 1/20 0.41
PDE4B Q07343 1/20 0.41
PDE4C Q08493 1/20 0.41
PDE4D Q08499 1/20 0.41
BCHE P06276 1/20 0.41
CYP3A4 P08684 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
BACE1 P56817 1/20 0.41
KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17735852 0.98 TSHR (0.44) CES2CES1TSHRKDM4EHPGD
SCHEMBL13580064 0.94 KDM4E (0.47) CES2CES1TSHRKDM4EHPGD
SCHEMBL21188357 0.89 KDM4E (0.53) CES2CES1TSHRKDM4EHPGD
SCHEMBL13609993 0.88 TRPA1 (0.57) KDM4EHPGDALDH1A1MAPTBCHE
SCHEMBL17489575 0.88 TRPA1 (0.57) KDM4EHPGDALDH1A1MAPTBCHE
SCHEMBL9777053 0.87 MAPT (0.53) CES2CES1KDM4EHPGDALDH1A1
SCHEMBL5036464 0.85 MEN1 (0.36) HPGDALDH1A1MAPTKMT2A
SCHEMBL12376989 0.85 MEN1 (0.36) HPGDALDH1A1MAPTKMT2A
SCHEMBL21188353 0.84 KDM4E (0.49) CES2CES1KDM4EHPGDALDH1A1
SCHEMBL18052485 0.84 TRPA1 (0.53) TSHRKDM4EHPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11287756-B2 Positive charging electrophotographic photoreceptor, electrophotographic cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-29 US disclosed
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
US-20100183332-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-07-22 US disclosed
US-20100183332-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-07-22 US disclosed