Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 8/20 | 1.00 |
| ▸ | PRKCG | P05129 | 8/20 | 1.00 |
| ▸ | PRKCB | P05771 | 8/20 | 1.00 |
| ▸ | PRKCA | P17252 | 8/20 | 1.00 |
| ▸ | PRKCH | P24723 | 8/20 | 1.00 |
| ▸ | PRKCI | P41743 | 8/20 | 1.00 |
| ▸ | PRKCE | Q02156 | 8/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 8/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 8/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 8/20 | 1.00 |
| ▸ | PRKD1 | Q15139 | 8/20 | 1.00 |
| ▸ | RAD52 | P43351 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | TNNI3 | P19429 | 1/20 | 1.00 |
| ▸ | APEX1 | P27695 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Corilagin SCHEMBL21026424 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Corilagin SCHEMBL14075996 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Corilagin SCHEMBL30208566 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Corilagin SCHEMBL29994662 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Corilagin SCHEMBL14089650 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Corilagin SCHEMBL18415304 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Corilagin SCHEMBL329080 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL20409294 | 0.93 | PRKD3 (0.88) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Strictinin SCHEMBL15262426 | 0.92 | RAD52 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Strictinin SCHEMBL17148972 | 0.92 | RAD52 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200315998-A1 | COMPOSITION FOR IMPROVING INTESTINAL BARRIER FUNCTION | SUNTORY HOLDINGS LIMITED (JP) | 2020-10-08 | — | — | US | disclosed |
| US-20180209956-A1 | HTS Assay for Identifying Small Molecule Inhibitors of RAD52 and Uses of Identified Small Molecule Inhibitors for Treatment and Prevention of BRCA-Deficient Malignancies | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2018-07-26 | — | — | US | disclosed |
| US-20170014362-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | CHATTERJEE SUBROTO (US) | 2017-01-19 | — | — | US | disclosed |
| US-20170014362-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | CHATTERJEE SUBROTO (US) | 2017-01-19 | — | — | US | disclosed |
| US-9376369-B2 | Anti-cholesterolemic compounds and methods of use | CHATTERJEE SUBROTO (US) | 2016-06-28 | — | — | US | disclosed |
| US-9376369-B2 | Anti-cholesterolemic compounds and methods of use | CHATTERJEE SUBROTO (US) | 2016-06-28 | — | — | US | disclosed |
| US-20140031304-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | CHATTERJEE SUBROTO (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031304-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | CHATTERJEE SUBROTO (US) | 2014-01-30 | — | — | US | disclosed |
| US-8492351-B2 | Anti-cholesterolemic compounds and methods of use | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2013-07-23 | — | — | US | disclosed |
| US-8492351-B2 | Anti-cholesterolemic compounds and methods of use | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2013-07-23 | — | — | US | disclosed |
| US-8366935-B2 | Phyllanthus extract | PHYTRIX INC. | 2013-02-05 | — | — | US | disclosed |
| US-8366935-B2 | Phyllanthus extract | PHYTRIX INC. | 2013-02-05 | — | — | US | disclosed |
| US-20100190726-A1 | Novel Phyllanthus Extract | PHYTRIX JV, LLC (US) | 2010-07-29 | — | — | US | disclosed |
| US-20100190726-A1 | Novel Phyllanthus Extract | PHYTRIX JV, LLC (US) | 2010-07-29 | — | — | US | disclosed |
| US-20100063153-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-03-11 | — | — | US | disclosed |
| US-20100063153-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200315998-A1 | COMPOSITION FOR IMPROVING INTESTINAL BARRIER FUNCTION | FABP2, SLC10A2, VIP | PRKD3 3966/4885PRKCG 1532/4885PRKCB 2383/4885 |
| US-20100190726-A1 | Novel Phyllanthus Extract | LRPPRC, PRLHR, PRRC2C | PRKD3 1036/4885PRKCG 577/4885PRKCB 846/4885 |
| US-20100063153-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | CETP, NPC1L1, HMGCR | PRKD3 3310/4885PRKCG 1424/4885PRKCB 1876/4885 |
| US-20180209956-A1 | HTS Assay for Identifying Small Molecule Inhibitors of RAD52 and Uses of Identified Small Molecule Inhibitors for Treatment and Prevention of BRCA-Deficient Malignancies | RAD52, BRCA1, RAD50 | PRKD3 867/4885PRKCG 1558/4885PRKCB 927/4885 |
| US-20140031304-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | CETP, NPC1L1, HMGCR | PRKD3 3310/4885PRKCG 1424/4885PRKCB 1876/4885 |
| US-20170014362-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | CETP, NPC1L1, HMGCR | PRKD3 3310/4885PRKCG 1424/4885PRKCB 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.