Corilagin

Corilagin

SCHEMBL14075996

O=C(O[C@@H]1OC2COC(=O)c3cc(O)c(O)c(O)c3-c3c(cc(O)c(O)c3O)C(=O)O[C@@H](C1O)[C@@H]2O)c1cc(O)c(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKD3 O94806 8/20 1.00
PRKCG P05129 8/20 1.00
PRKCB P05771 8/20 1.00
PRKCA P17252 8/20 1.00
PRKCH P24723 8/20 1.00
PRKCI P41743 8/20 1.00
PRKCE Q02156 8/20 1.00
PRKCQ Q04759 8/20 1.00
PRKCZ Q05513 8/20 1.00
PRKCD Q05655 8/20 1.00
PRKD1 Q15139 8/20 1.00
RAD52 P43351 2/20 1.00
USP2 O75604 1/20 1.00
LMNA P02545 1/20 1.00
POLB P06746 1/20 1.00
GAA P10253 1/20 1.00
MAPT P10636 1/20 1.00
HPGD P15428 1/20 1.00
TNNI3 P19429 1/20 1.00
APEX1 P27695 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Corilagin SCHEMBL21026424 1.00 PRKD3 (1.00) PRKD3PRKCGPRKCBPRKCAPRKCH
Corilagin SCHEMBL30208566 1.00 PRKD3 (1.00) PRKD3PRKCGPRKCBPRKCAPRKCH
Corilagin SCHEMBL29994662 1.00 PRKD3 (1.00) PRKD3PRKCGPRKCBPRKCAPRKCH
Corilagin SCHEMBL14089650 1.00 PRKD3 (1.00) PRKD3PRKCGPRKCBPRKCAPRKCH
Corilagin SCHEMBL18415304 1.00 PRKD3 (1.00) PRKD3PRKCGPRKCBPRKCAPRKCH
Corilagin SCHEMBL329080 1.00 PRKD3 (1.00) PRKD3PRKCGPRKCBPRKCAPRKCH
Corilagin SCHEMBL13242674 1.00 PRKD3 (1.00) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL20409294 0.93 PRKD3 (0.88) PRKD3PRKCGPRKCBPRKCAPRKCH
Strictinin SCHEMBL15262426 0.92 RAD52 (1.00) PRKD3PRKCGPRKCBPRKCAPRKCH
Strictinin SCHEMBL17148972 0.92 RAD52 (1.00) PRKD3PRKCGPRKCBPRKCAPRKCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130122119-A1 PHYLLANTHUS AMARUS COMPOSITIONS AND METHOD OF EXTRACTING SAME NATREON, INC. (US) 2013-05-16 US disclosed
US-20080214656-A1 Compounds With Diphenoyl-Structure For the Treatment of Immune Diseases NEUROGENEX CO., LTD. (KR) 2008-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214656-A1 Compounds With Diphenoyl-Structure For the Treatment of Immune Diseases HLA-DRB1, CD4, NFATC1 PRKD3 754/4885PRKCG 2572/4885PRKCB 2643/4885
US-20130122119-A1 PHYLLANTHUS AMARUS COMPOSITIONS AND METHOD OF EXTRACTING SAME AAAS, CALU, ARGLU1 PRKD3 1559/4885PRKCG 2679/4885PRKCB 3486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.