SCHEMBL13243191

SCHEMBL13243191

CCC(C)C(=O)Nc1ccc(Cc2ccc(NC(=O)C(C)(C)CC)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA7 P43166 3/20 0.50
CA14 Q9ULX7 3/20 0.50
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
HSD17B10 Q99714 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SPHK1 Q9NYA1 1/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
BRD4 O60885 1/20 0.39
SAE1 Q9UBE0 1/20 0.38
UBA2 Q9UBT2 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10075598 0.87 MEN1 (0.53) MEN1KMT2ATDP1L3MBTL1LMNA
SCHEMBL22002689 0.87 CA1 (0.62) CA1CA2CA7CA14MEN1
SCHEMBL6807344 0.83 L3MBTL1 (0.61) CA1CA2CA7CA14MEN1
SCHEMBL18291139 0.81 MEN1 (0.48) MEN1KMT2ATDP1L3MBTL1LMNA
SCHEMBL13450062 0.81 KMT2A (0.51) CA1CA2MEN1KMT2ATDP1
SCHEMBL23008479 0.81 SPHK1 (0.46) CA1CA2MEN1KMT2ATDP1
SCHEMBL8946141 0.80 MEN1 (0.66) MEN1KMT2ATDP1L3MBTL1NPC1
SCHEMBL12226380 0.79 L3MBTL1 (0.61) CA1CA2CA7CA14MEN1
SCHEMBL24296447 0.78 CA1 (0.52) CA1CA2CA7CA14MEN1
SCHEMBL24296342 0.77 HPGD (0.52) CA1CA2CA7CA14MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4397502-A1 ON-MACHINE DEVELOPMENT-TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR MANUFACTURING PRINTING PLATE FUJIFILM Corporation (JP) 2024-07-10 EP disclosed
EP-4269122-A1 LAMINATE OF NEGATIVE LITHOGRAPHIC PRINTING PLATE ORIGINAL PLATE AND METHOD FOR MANUFACTURING NEGATIVE LITHOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2023-11-01 EP disclosed
US-7771916-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-08-10 US disclosed
US-20100075061-A1 INK COMPOSITION, INKJET RECORDING METHOD AND METHOD FOR PRODUCING PRINTED FORMED ARTICLE FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed