Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | ACACB | O00763 | 3/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13984845 | 1.00 | HDAC1 (0.55) | HDAC1ACACBPDE4APDE4BPDE4C | |
| SCHEMBL13984851 | 0.98 | HDAC1 (0.52) | HDAC1ACACB | |
| SCHEMBL13245385 | 0.98 | HDAC1 (0.52) | HDAC1ACACB | |
| SCHEMBL13984843 | 0.96 | HDAC1 (0.48) | HDAC1ACACB | |
| SCHEMBL18023375 | 0.96 | HDAC1 (0.48) | HDAC1ACACB | |
| SCHEMBL13245354 | 0.96 | HDAC1 (0.48) | HDAC1ACACB | |
| SCHEMBL13245516 | 0.96 | HDAC1 (0.48) | HDAC1ACACB | |
| SCHEMBL13245032 | 0.92 | HDAC1 (0.46) | HDAC1 | |
| SCHEMBL405819 | 0.91 | HDAC1 (0.56) | HDAC1ACACB | |
| SCHEMBL13267409 | 0.91 | HDAC1 (0.58) | HDAC1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | HDAC1 702/4885ACACB 3224/4885PDE4A 1601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.