SCHEMBL1324800

SCHEMBL1324800

c1nncc2cnncc12

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
CDC25B P30305 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13156493 0.77 ALDH1A1 (0.50) ALDH1A1
SCHEMBL16878359 0.71
Phthalazine SCHEMBL15264828 0.71 CYP2A6 (0.47) ALDH1A1
Phthalazine SCHEMBL5675695 0.71 CYP2A6 (0.47) ALDH1A1
SCHEMBL9666642 0.69 ALDH1A1 (0.43) ALDH1A1
SCHEMBL8404447 0.69 ALDH1A1 (0.50) ALDH1A1
SCHEMBL29846477 0.67 CDC25B (0.30) CDC25B
SCHEMBL30574445 0.67 CDC25B (0.30) CDC25B
SCHEMBL6278613 0.60
SCHEMBL18507837 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11786600-B2 Cliptac composition OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2023-10-17 US claimed
US-20190275161-A1 CLIPTAC COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2019-09-12 US claimed
WO-2017212329-A1 CLIPTAC COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2017-12-14 WO claimed
EP-0145337-B1 ELECTROCHROMIC DEVICES CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1990-08-08 EP claimed
EP-0096723-B1 BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-08-10 EP claimed
US-4613211-A REVERSE COLOR CHANGING POLYMER FILM AS DISPLAY ELECTRODE CHEVRON RESEARCH COMPANY (US) 1986-09-23 US claimed
US-4579679-A Electroactive polymers CHEVRON RESEARCH COMPANY (US) 1986-04-01 US claimed
EP-0145337-A2 Electrochromic devices CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1985-06-19 EP claimed
US-20240131169-A1 CLIPTAC COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-04-25 US disclosed
US-11786600-B2 Cliptac composition OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2023-10-17 US disclosed
US-20210038748-A1 Compositions And Methods For In Vivo Imaging THE GENERAL HOSPITAL CORPORATION 2021-02-11 US disclosed
EP-3052506-B1 AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES FLEXENABLE LTD (GB) 2020-06-03 EP disclosed
US-10653805-B2 Compositions and methods for in vivo imaging THE GENERAL HOSPITAL CORPORATION (US) 2020-05-19 US disclosed
EP-3622968-A1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET The General Hospital Corporation (US) 2020-03-18 EP disclosed
EP-0145337-B1 ELECTROCHROMIC DEVICES CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1990-08-08 EP disclosed
US-4613211-A REVERSE COLOR CHANGING POLYMER FILM AS DISPLAY ELECTRODE CHEVRON RESEARCH COMPANY (US) 1986-09-23 US disclosed
US-4579679-A Electroactive polymers CHEVRON RESEARCH COMPANY (US) 1986-04-01 US disclosed
EP-0145337-A2 Electrochromic devices CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1985-06-19 EP disclosed
US-4519937-A DOPED UNITS OF A FUSED NITROGEN-CONTAINING UNSATURATED HETEROCYCLIC RING CHEVRON RESEARCH COMPANY (US) 1985-05-28 US disclosed
US-4519938-A TRACTABLE, DOPED HETEROCYCLIC RINGS CHEVRON RESEARCH COMPANY (US) 1985-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210038748-A1 Compositions And Methods For In Vivo Imaging PARP1, PARP11, PARP2 ALDH1A1 3017/4885CDC25B 3798/4885
US-11786600-B2 Cliptac composition UBE3C, CBLC, STUB1 ALDH1A1 3352/4885CDC25B 2648/4885
US-20190275161-A1 CLIPTAC COMPOSITION UBE3C, CBLC, STUB1 ALDH1A1 3352/4885CDC25B 2648/4885
US-20240131169-A1 CLIPTAC COMPOSITION UBE3C, CBLC, STUB1 ALDH1A1 3352/4885CDC25B 2648/4885
US-10653805-B2 Compositions and methods for in vivo imaging PARP1, PARP11, PARP2 ALDH1A1 3017/4885CDC25B 3798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.