Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | ATM | Q13315 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.61 |
| ▸ | GBA1 | P04062 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524273 | 0.93 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL15298984 | 0.92 | MAOB (0.63) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13248269 | 0.91 | KMT2A (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14948237 | 0.90 | KMT2A (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13248272 | 0.90 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3174736 | 0.90 | KMT2A (0.65) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9303724 | 0.89 | KMT2A (0.70) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9302597 | 0.88 | KMT2A (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14820431 | 0.87 | KMT2A (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17612195 | 0.87 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247710-B1 | COUMARIN-BASED COMPOUNDS AND RELATED METHODS | BIOSEARCH TECH INC (US) | 2022-10-19 | — | — | EP | disclosed |
| CN-107207480-B | Coumarin-based compounds and related methods | 生物检索技术股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| US-11034677-B2 | Coumarin-based compounds and related methods | BIOSEARCH TECHNOLOGIES, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| US-11034677-B2 | Coumarin-based compounds and related methods | BIOSEARCH TECHNOLOGIES, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| EP-3247710-A1 | COUMARIN-BASED COMPOUNDS AND RELATED METHODS | Biosearch Technologies, Inc. (US) | 2017-11-29 | — | — | EP | disclosed |
| US-20170015652-A1 | Coumarin-based compounds and related methods | BIOSEARCH TECHNOLOGIES, INC. | 2017-01-19 | — | — | US | disclosed |
| US-20170015652-A1 | Coumarin-based compounds and related methods | BIOSEARCH TECHNOLOGIES, INC. | 2017-01-19 | — | — | US | disclosed |
| US-20170015652-A1 | Coumarin-based compounds and related methods | BIOSEARCH TECHNOLOGIES, INC. | 2017-01-19 | — | — | US | disclosed |
| WO-2016118305-A1 | COUMARIN-BASED COMPOUNDS AND RELATED METHODS | BIOSEARCH TECHNOLOGIES, INC. (US) | 2016-07-28 | — | — | WO | disclosed |
| WO-2016118305-A1 | COUMARIN-BASED COMPOUNDS AND RELATED METHODS | BIOSEARCH TECHNOLOGIES, INC. (US) | 2016-07-28 | — | — | WO | disclosed |
| US-8846320-B2 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20100184087-A1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. | 2010-07-22 | — | — | US | disclosed |
| US-7695929-B2 | Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits | VENTANA MEDICAL SYSTEMS, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| US-20080268462-A1 | Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits | VENTANA MEDICAL SYSTEMS, INC. | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080268462-A1 | Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits | HRH4, CRBN, NCDN | KMT2A 3827/4885MEN1 4162/4885ALDH1A1 2096/4885 |
| US-11034677-B2 | Coumarin-based compounds and related methods | HCCS, FBL, COIL | KMT2A 3163/4885MEN1 2472/4885ALDH1A1 990/4885 |
| US-20170015652-A1 | Coumarin-based compounds and related methods | HCCS, FBL, COIL | KMT2A 3163/4885MEN1 2472/4885ALDH1A1 990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.