Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.59 |
| ▸ | GBA1 | P04062 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15298984 | 0.92 | MAOB (0.63) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13524273 | 0.91 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13248271 | 0.90 | KMT2A (0.61) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17612195 | 0.89 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13248269 | 0.89 | KMT2A (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13248272 | 0.88 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3174736 | 0.88 | KMT2A (0.65) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16202224 | 0.87 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9302597 | 0.86 | KMT2A (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14820431 | 0.85 | KMT2A (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130122516-A1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MEDICAL SYSTEMS, INC. | 2013-05-16 | — | — | US | disclosed |
| US-20130122516-A1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MEDICAL SYSTEMS, INC. | 2013-05-16 | — | — | US | disclosed |